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Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models.
Nat Commun. 2024 Mar 11;15(1):2192. doi: 10.1038/s41467-024-46167-1.
Nat Commun. 2024.
PMID: 38467634
Free PMC article.
Total Synthesis of (-)-Morphine.
Umihara H, Yokoshima S, Inoue M, Fukuyama T.
Umihara H, et al.
Chemistry. 2017 May 23;23(29):6993-6995. doi: 10.1002/chem.201701438. Epub 2017 Apr 25.
Chemistry. 2017.
PMID: 28378531
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Eudistomin C, an Antitumor and Antiviral Natural Product, Targets 40S Ribosome and Inhibits Protein Translation.
Ota Y, Chinen T, Yoshida K, Kudo S, Nagumo Y, Shiwa Y, Yamada R, Umihara H, Iwasaki K, Masumoto H, Yokoshima S, Yoshikawa H, Fukuyama T, Kobayashi J, Usui T.
Ota Y, et al. Among authors: umihara h.
Chembiochem. 2016 Sep 2;17(17):1616-20. doi: 10.1002/cbic.201600075. Epub 2016 Jul 22.
Chembiochem. 2016.
PMID: 27304596
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Antiproliferative Activity of Amathaspiramide Alkaloids and Analogs.
Shimokawa J, Chiyoda K, Umihara H, Fukuyama T.
Shimokawa J, et al. Among authors: umihara h.
Chem Pharm Bull (Tokyo). 2016 Aug 1;64(8):1239-41. doi: 10.1248/cpb.c16-00256. Epub 2016 May 10.
Chem Pharm Bull (Tokyo). 2016.
PMID: 27169437
Free article.
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Development of a Divergent Synthetic Route to the Erythrina Alkaloids: Asymmetric Syntheses of 8-Oxo-erythrinine, Crystamidine, 8-Oxo-erythraline, and Erythraline.
Umihara H, Yoshino T, Shimokawa J, Kitamura M, Fukuyama T.
Umihara H, et al.
Angew Chem Int Ed Engl. 2016 Jun 6;55(24):6915-8. doi: 10.1002/anie.201602650. Epub 2016 May 4.
Angew Chem Int Ed Engl. 2016.
PMID: 27145193
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Conversion of Ester Moieties to 4-Bromophenyl Groups via Electrocyclic Reaction of Dibromocyclopropanes.
Ueda K, Umihara H, Yokoshima S, Fukuyama T.
Ueda K, et al. Among authors: umihara h.
Org Lett. 2015 Jul 2;17(13):3191-3. doi: 10.1021/acs.orglett.5b01351. Epub 2015 Jun 12.
Org Lett. 2015.
PMID: 26065731
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Synthesis of (-)-oxycodone.
Kimishima A, Umihara H, Mizoguchi A, Yokoshima S, Fukuyama T.
Kimishima A, et al. Among authors: umihara h.
Org Lett. 2014 Dec 5;16(23):6244-7. doi: 10.1021/ol503175n. Epub 2014 Nov 25.
Org Lett. 2014.
PMID: 25423610
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