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Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein.
J Med Chem. 2024 Mar 28;67(6):4936-4949. doi: 10.1021/acs.jmedchem.4c00078. Epub 2024 Mar 13.
J Med Chem. 2024.
PMID: 38477582
Free PMC article.
Stereoselective Amine Synthesis Mediated by a Zirconocene Hydride to Accelerate a Drug Discovery Program.
Aloiau AN, Bobek BM, Caddell Haatveit K, Pearson KE, Watkins AH, Jones B, Smith CR, Ketcham JM, Marx MA, Harwood SJ.
Aloiau AN, et al. Among authors: caddell haatveit k.
J Org Chem. 2024 Mar 15;89(6):3875-3882. doi: 10.1021/acs.joc.3c02723. Epub 2024 Feb 29.
J Org Chem. 2024.
PMID: 38422508
Free PMC article.
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A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases.
Hoffarth ER, Caddell Haatveit K, Kuatsjah E, MacNeil GA, Saroya S, Walsby CJ, Eltis LD, Houk KN, Garcia-Borràs M, Ryan KS.
Hoffarth ER, et al. Among authors: caddell haatveit k.
Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2012591118. doi: 10.1073/pnas.2012591118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34580201
Free PMC article.
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Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
Fraley AE, Caddell Haatveit K, Ye Y, Kelly SP, Newmister SA, Yu F, Williams RM, Smith JL, Houk KN, Sherman DH.
Fraley AE, et al. Among authors: caddell haatveit k.
J Am Chem Soc. 2020 Feb 5;142(5):2244-2252. doi: 10.1021/jacs.9b09070. Epub 2020 Jan 16.
J Am Chem Soc. 2020.
PMID: 31904957
Free PMC article.
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Computational Protocol to Understand P450 Mechanisms and Design of Efficient and Selective Biocatalysts.
Caddell Haatveit K, Garcia-Borràs M, Houk KN.
Caddell Haatveit K, et al.
Front Chem. 2019 Jan 11;6:663. doi: 10.3389/fchem.2018.00663. eCollection 2018.
Front Chem. 2019.
PMID: 30687699
Free PMC article.
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