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G protein-coupled receptor (GPCR) gene variants and human genetic disease.
Thompson MD, Percy ME, Cole DEC, Bichet DG, Hauser AS, Gorvin CM. Thompson MD, et al. Among authors: hauser as. Crit Rev Clin Lab Sci. 2024 Mar 18:1-30. doi: 10.1080/10408363.2023.2286606. Online ahead of print. Crit Rev Clin Lab Sci. 2024. PMID: 38497103 Review.
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE. Hauser AS, et al. Nat Rev Drug Discov. 2017 Dec;16(12):829-842. doi: 10.1038/nrd.2017.178. Epub 2017 Oct 27. Nat Rev Drug Discov. 2017. PMID: 29075003 Free PMC article. Review.
Common coupling map advances GPCR-G protein selectivity.
Hauser AS, Avet C, Normand C, Mancini A, Inoue A, Bouvier M, Gloriam DE. Hauser AS, et al. Elife. 2022 Mar 18;11:e74107. doi: 10.7554/eLife.74107. Elife. 2022. PMID: 35302494 Free PMC article.
GPCRdb: the G protein-coupled receptor database - an introduction.
Munk C, Isberg V, Mordalski S, Harpsøe K, Rataj K, Hauser AS, Kolb P, Bojarski AJ, Vriend G, Gloriam DE. Munk C, et al. Among authors: hauser as. Br J Pharmacol. 2016 Jul;173(14):2195-207. doi: 10.1111/bph.13509. Epub 2016 Jun 3. Br J Pharmacol. 2016. PMID: 27155948 Free PMC article. Review.
Selectivity determinants of GPCR-G-protein binding.
Flock T, Hauser AS, Lund N, Gloriam DE, Balaji S, Babu MM. Flock T, et al. Among authors: hauser as. Nature. 2017 May 18;545(7654):317-322. doi: 10.1038/nature22070. Epub 2017 May 10. Nature. 2017. PMID: 28489817 Free PMC article.
Mutational Landscape of the Proglucagon-Derived Peptides.
Lindquist P, Madsen JS, Bräuner-Osborne H, Rosenkilde MM, Hauser AS. Lindquist P, et al. Among authors: hauser as. Front Endocrinol (Lausanne). 2021 Jun 17;12:698511. doi: 10.3389/fendo.2021.698511. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34220721 Free PMC article.
GPCR activation mechanisms across classes and macro/microscales.
Hauser AS, Kooistra AJ, Munk C, Heydenreich FM, Veprintsev DB, Bouvier M, Babu MM, Gloriam DE. Hauser AS, et al. Nat Struct Mol Biol. 2021 Nov;28(11):879-888. doi: 10.1038/s41594-021-00674-7. Epub 2021 Nov 10. Nat Struct Mol Biol. 2021. PMID: 34759375 Free PMC article.
35 results