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Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.
Fujita M, Gao Z, Zeng L, McCabe C, White CC, Ng B, Green GS, Rozenblatt-Rosen O, Phillips D, Amir-Zilberstein L, Lee H, Pearse RV 2nd, Khan A, Vardarajan BN, Kiryluk K, Ye CJ, Klein HU, Wang G, Regev A, Habib N, Schneider JA, Wang Y, Young-Pearse T, Mostafavi S, Bennett DA, Menon V, De Jager PL. Fujita M, et al. Among authors: klein hu. Nat Genet. 2024 Apr;56(4):605-614. doi: 10.1038/s41588-024-01685-y. Epub 2024 Mar 21. Nat Genet. 2024. PMID: 38514782
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL. Mostafavi S, et al. Among authors: klein hu. Nat Neurosci. 2018 Jun;21(6):811-819. doi: 10.1038/s41593-018-0154-9. Epub 2018 May 25. Nat Neurosci. 2018. PMID: 29802388 Free PMC article.
UNC5C variants are associated with cerebral amyloid angiopathy.
Yang HS, White CC, Chibnik LB, Klein HU, Schneider JA, Bennett DA, De Jager PL. Yang HS, et al. Among authors: klein hu. Neurol Genet. 2017 Jul 18;3(4):e176. doi: 10.1212/NXG.0000000000000176. eCollection 2017 Aug. Neurol Genet. 2017. PMID: 28761931 Free PMC article.
Tau Activates Transposable Elements in Alzheimer's Disease.
Guo C, Jeong HH, Hsieh YC, Klein HU, Bennett DA, De Jager PL, Liu Z, Shulman JM. Guo C, et al. Among authors: klein hu. Cell Rep. 2018 Jun 5;23(10):2874-2880. doi: 10.1016/j.celrep.2018.05.004. Cell Rep. 2018. PMID: 29874575 Free PMC article.
A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA. De Jager PL, et al. Among authors: klein hu. Sci Data. 2018 Aug 7;5:180142. doi: 10.1038/sdata.2018.142. Sci Data. 2018. PMID: 30084846 Free PMC article.
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL. Klein HU, et al. Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559478 Free PMC article.
249 results