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The Alzheimer's disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons.
Saha O, Melo de Farias AR, Pelletier A, Siedlecki-Wullich D, Landeira BS, Gadaut J, Carrier A, Vreulx AC, Guyot K, Shen Y, Bonnefond A, Amouyel P, Tcw J, Kilinc D, Queiroz CM, Delahaye F, Lambert JC, Costa MR. Saha O, et al. Among authors: costa mr. Mol Psychiatry. 2024 Mar 22. doi: 10.1038/s41380-024-02502-y. Online ahead of print. Mol Psychiatry. 2024. PMID: 38514804
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects.
Lambert E, Saha O, Soares Landeira B, Melo de Farias AR, Hermant X, Carrier A, Pelletier A, Gadaut J, Davoine L, Dupont C, Amouyel P, Bonnefond A, Lafont F, Abdelfettah F, Verstreken P, Chapuis J, Barois N, Delahaye F, Dermaut B, Lambert JC, Costa MR, Dourlen P. Lambert E, et al. Among authors: costa mr. Acta Neuropathol Commun. 2022 Jan 8;10(1):4. doi: 10.1186/s40478-021-01285-5. Acta Neuropathol Commun. 2022. PMID: 34998435 Free PMC article.
Pyk2 overexpression in postsynaptic neurons blocks amyloid β1-42-induced synaptotoxicity in microfluidic co-cultures.
Kilinc D, Vreulx AC, Mendes T, Flaig A, Marques-Coelho D, Verschoore M, Demiautte F, Amouyel P; Neuro-CEB Brain Bank; Eysert F, Dourlen P, Chapuis J, Costa MR, Malmanche N, Checler F, Lambert JC. Kilinc D, et al. Among authors: costa mr. Brain Commun. 2020 Aug 28;2(2):fcaa139. doi: 10.1093/braincomms/fcaa139. eCollection 2020. Brain Commun. 2020. PMID: 33718872 Free PMC article.
227 results