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Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma.
Nat Commun. 2024 Mar 22;15(1):2581. doi: 10.1038/s41467-024-46835-2.
Nat Commun. 2024.
PMID: 38519484
Free PMC article.
Multiparametric Analyses of Hepatocellular Carcinoma Somatic Mouse Models and Their Associated Tumor Microenvironment.
Taranto D, Ramirez CFA, Vegna S, de Groot MHP, de Wit N, Van Baalen M, Klarenbeek S, Akkari L.
Taranto D, et al. Among authors: ramirez cfa.
Curr Protoc. 2021 Jun;1(6):e147. doi: 10.1002/cpz1.147.
Curr Protoc. 2021.
PMID: 34101385
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EGFR activation limits the response of liver cancer to lenvatinib.
Jin H, Shi Y, Lv Y, Yuan S, Ramirez CFA, Lieftink C, Wang L, Wang S, Wang C, Dias MH, Jochems F, Yang Y, Bosma A, Hijmans EM, de Groot MHP, Vegna S, Cui D, Zhou Y, Ling J, Wang H, Guo Y, Zheng X, Isima N, Wu H, Sun C, Beijersbergen RL, Akkari L, Zhou W, Zhai B, Qin W, Bernards R.
Jin H, et al. Among authors: ramirez cfa.
Nature. 2021 Jul;595(7869):730-734. doi: 10.1038/s41586-021-03741-7. Epub 2021 Jul 21.
Nature. 2021.
PMID: 34290403
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Inducing and exploiting vulnerabilities for the treatment of liver cancer.
Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, de Oliveira RL, Morris B, Gadiot J, Wang W, du Chatinier A, Wang L, Gao D, Evers B, Jin G, Xue Z, Schepers A, Jochems F, Sanchez AM, Mainardi S, Te Riele H, Beijersbergen RL, Qin W, Akkari L, Bernards R.
Wang C, et al.
Nature. 2019 Oct;574(7777):268-272. doi: 10.1038/s41586-019-1607-3. Epub 2019 Oct 2.
Nature. 2019.
PMID: 31578521
Free PMC article.
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Understanding the Origin and Diversity of Macrophages to Tailor Their Targeting in Solid Cancers.
Kielbassa K, Vegna S, Ramirez C, Akkari L.
Kielbassa K, et al.
Front Immunol. 2019 Sep 25;10:2215. doi: 10.3389/fimmu.2019.02215. eCollection 2019.
Front Immunol. 2019.
PMID: 31611871
Free PMC article.
Review.
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Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.
Mulero-Sánchez A, Ramirez CFA, du Chatinier A, Wang H, Koomen SJI, Song JY, de Groot MHP, Lieftink C, Bosma A, Burylo A, van Tellingen O, Beijersbergen RL, Wang C, Akkari L, Bernards R, Mainardi S.
Mulero-Sánchez A, et al. Among authors: ramirez cfa.
Mol Oncol. 2023 Jun;17(6):964-980. doi: 10.1002/1878-0261.13377. Epub 2023 Feb 9.
Mol Oncol. 2023.
PMID: 36650715
Free PMC article.
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Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of hepatocellular carcinoma.
Lozano A, Souche FR, Chavey C, Dardalhon V, Ramirez C, Vegna S, Desandre G, Riviere A, Zine El Aabidine A, Fort P, Akkari L, Hibner U, Grégoire D.
Lozano A, et al.
Elife. 2023 Jan 19;12:e76294. doi: 10.7554/eLife.76294.
Elife. 2023.
PMID: 36656749
Free PMC article.
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