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211 results

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Gain-of-function IKBKB mutation causes human combined immune deficiency.
Cardinez C, Miraghazadeh B, Tanita K, da Silva E, Hoshino A, Okada S, Chand R, Asano T, Tsumura M, Yoshida K, Ohnishi H, Kato Z, Yamazaki M, Okuno Y, Miyano S, Kojima S, Ogawa S, Andrews TD, Field MA, Burgio G, Morio T, Vinuesa CG, Kanegane H, Cook MC. Cardinez C, et al. Among authors: chand r. J Exp Med. 2018 Nov 5;215(11):2715-2724. doi: 10.1084/jem.20180639. Epub 2018 Oct 18. J Exp Med. 2018. PMID: 30337470 Free PMC article.
CTLA4 protects against maladaptive cytotoxicity during the differentiation of effector and follicular CD4+ T cells.
Hao Y, Miraghazadeh B, Chand R, Davies AR, Cardinez C, Kwong K, Downes MB, Sweet RA, Cañete PF, D'Orsogna LJ, Fulcher DA, Choo S, Yip D, Peters G, Yip S, Witney MJ, Nekrasov M, Feng ZP, Tscharke DC, Vinuesa CG, Cook MC. Hao Y, et al. Among authors: chand r. Cell Mol Immunol. 2023 Jul;20(7):777-793. doi: 10.1038/s41423-023-01027-8. Epub 2023 May 9. Cell Mol Immunol. 2023. PMID: 37161048 Free PMC article.
STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles.
Alshekaili J, Chand R, Lee CE, Corley S, Kwong K, Papa I, Fulcher DA, Randall KL, Leiding JW, Ma CS, Wilkins MR, Uzel G, Goodnow CC, Vinuesa CG, Tangye SG, Cook MC. Alshekaili J, et al. Among authors: chand r. Sci Rep. 2018 Feb 23;8(1):3529. doi: 10.1038/s41598-018-21389-8. Sci Rep. 2018. PMID: 29476109 Free PMC article.
Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.
Ellyard JI, Tunningley R, Lorenzo AM, Jiang SH, Cook A, Chand R, Talaulikar D, Hatch AM, Wilson A, Vinuesa CG, Cook MC, Fulcher DA. Ellyard JI, et al. Among authors: chand r. Front Immunol. 2019 Sep 11;10:2134. doi: 10.3389/fimmu.2019.02134. eCollection 2019. Front Immunol. 2019. PMID: 31572362 Free PMC article. Clinical Trial.
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.
Wirasinha RC, Davies AR, Srivastava M, Sheridan JM, Sng XYX, Delmonte OM, Dobbs K, Loh KL, Miosge LA, Lee CE, Chand R, Chan A, Yap JY, Keller MD, Chen K, Rossjohn J, La Gruta NL, Vinuesa CG, Reid HH, Lionakis MS, Notarangelo LD, Gray DHD, Goodnow CC, Cook MC, Daley SR. Wirasinha RC, et al. Among authors: chand r. J Exp Med. 2021 Feb 1;218(2):e20200476. doi: 10.1084/jem.20200476. J Exp Med. 2021. PMID: 33107914 Free PMC article.
Extraction of tissue antigens for functional assays.
Necula A, Chand R, Albatat B, Mannering SI. Necula A, et al. Among authors: chand r. J Vis Exp. 2012 Sep 10;(67):4230. doi: 10.3791/4230. J Vis Exp. 2012. PMID: 22986305 Free PMC article.
211 results