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Paradoxical activation of oncogenic signaling as a cancer treatment strategy.
Cancer Discov. 2024 Mar 27. doi: 10.1158/2159-8290.CD-23-0216. Online ahead of print.
Cancer Discov. 2024.
PMID: 38533987
Centriole structural integrity defects are a crucial feature of Hydrolethalus Syndrome.
Curinha A, Huang Z, Anglen T, Strong MA, Gliech CR, Jewett CE, Friskes A, Holland AJ.
Curinha A, et al. Among authors: friskes a.
bioRxiv [Preprint]. 2024 Mar 6:2024.03.06.583733. doi: 10.1101/2024.03.06.583733.
bioRxiv. 2024.
PMID: 38496445
Free PMC article.
Preprint.
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Perturbations in 3D genome organization can promote acquired drug resistance.
Manjón AG, Manzo SG, Prekovic S, Potgeter L, van Schaik T, Liu NQ, Flach K, Peric-Hupkes D, Joosten S, Teunissen H, Friskes A, Ilic M, Hintzen D, Franceschini-Santos VH, Zwart W, de Wit E, van Steensel B, Medema RH.
Manjón AG, et al. Among authors: friskes a.
Cell Rep. 2023 Oct 31;42(10):113124. doi: 10.1016/j.celrep.2023.113124. Epub 2023 Sep 20.
Cell Rep. 2023.
PMID: 37733591
Free article.
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MND1 enables homologous recombination in somatic cells primarily outside the context of replication.
Koob L, Friskes A, van Bergen L, Feringa FM, van den Broek B, Koeleman ES, van Beek E, Schubert M, Blomen VA, Brummelkamp TR, Krenning L, Medema RH.
Koob L, et al. Among authors: friskes a.
Mol Oncol. 2023 Jul;17(7):1192-1211. doi: 10.1002/1878-0261.13448. Epub 2023 Jun 14.
Mol Oncol. 2023.
PMID: 37195379
Free PMC article.
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Double-strand break toxicity is chromatin context independent.
Friskes A, Koob L, Krenning L, Severson TM, Koeleman ES, Vergara X, Schubert M, van den Berg J, Evers B, Manjón AG, Joosten S, Kim Y, Zwart W, Medema RH.
Friskes A, et al.
Nucleic Acids Res. 2022 Sep 23;50(17):9930-9947. doi: 10.1093/nar/gkac758.
Nucleic Acids Res. 2022.
PMID: 36107780
Free PMC article.
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Unexpected gene activation following CRISPR-Cas9-mediated genome editing.
Manjón AG, Linder S, Teunissen H, Friskes A, Zwart W, de Wit E, Medema RH.
Manjón AG, et al. Among authors: friskes a.
EMBO Rep. 2022 Feb 3;23(2):e53902. doi: 10.15252/embr.202153902. Epub 2021 Dec 20.
EMBO Rep. 2022.
PMID: 34927791
Free PMC article.
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