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Contractile and Genetic Characterization of Cardiac Constructs Engineered from Human Induced Pluripotent Stem Cells: Modeling of Tuberous Sclerosis Complex and the Effects of Rapamycin.
Sidorov VY, Sidorova TN, Samson PC, Reiserer RS, Britt CM, Neely MD, Ess KC, Wikswo JP. Sidorov VY, et al. Among authors: britt cm. Bioengineering (Basel). 2024 Feb 28;11(3):234. doi: 10.3390/bioengineering11030234. Bioengineering (Basel). 2024. PMID: 38534508 Free PMC article.
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor.
Brown JA, Pensabene V, Markov DA, Allwardt V, Neely MD, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, Bowman AB, Reiserer RS, Wikswo JP. Brown JA, et al. Among authors: britt cm. Biomicrofluidics. 2015 Oct 26;9(5):054124. doi: 10.1063/1.4934713. eCollection 2015 Sep. Biomicrofluidics. 2015. PMID: 26576206 Free PMC article.
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit.
Brown JA, Codreanu SG, Shi M, Sherrod SD, Markov DA, Neely MD, Britt CM, Hoilett OS, Reiserer RS, Samson PC, McCawley LJ, Webb DJ, Bowman AB, McLean JA, Wikswo JP. Brown JA, et al. Among authors: britt cm. J Neuroinflammation. 2016 Dec 12;13(1):306. doi: 10.1186/s12974-016-0760-y. J Neuroinflammation. 2016. PMID: 27955696 Free PMC article.
A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models.
Singh D, Deosarkar SP, Cadogan E, Flemington V, Bray A, Zhang J, Reiserer RS, Schaffer DK, Gerken GB, Britt CM, Werner EM, Gibbons FD, Kostrzewski T, Chambers CE, Davies EJ, Montoya AR, Fok JHL, Hughes D, Fabre K, Wagoner MP, Wikswo JP, Scott CW. Singh D, et al. Among authors: britt cm. PLoS Biol. 2022 May 26;20(5):e3001624. doi: 10.1371/journal.pbio.3001624. eCollection 2022 May. PLoS Biol. 2022. PMID: 35617197 Free PMC article.