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Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
Li J, Hilimire TA, Liu Y, Wang L, Liang J, Gyorffy B, Sikirzhytski V, Ji H, Zhang L, Cheng C, Ding X, Kerr KR, Dowling CE, Chumanevich AA, Mack ZT, Schools GP, Lim CU, Ellis L, Zi X, Porter DC, Broude EV, McInnes C, Wilding G, Lilly MB, Roninson IB, Chen M. Li J, et al. Among authors: zhang l. J Clin Invest. 2024 Mar 28;134(10):e176709. doi: 10.1172/JCI176709. J Clin Invest. 2024. PMID: 38546787 Free PMC article.
CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.
Chen M, Li J, Zhang L, Wang L, Cheng C, Ji H, Altilia S, Ding X, Cai G, Altomare D, Shtutman M, Byrum SD, Mackintosh SG, Feoktistov A, Soshnikova N, Mogila VA, Tatarskiy V, Erokhin M, Chetverina D, Prawira A, Ni Y, Urban S, McInnes C, Broude EV, Roninson IB. Chen M, et al. Among authors: zhang l. Nucleic Acids Res. 2023 Aug 11;51(14):7288-7313. doi: 10.1093/nar/gkad538. Nucleic Acids Res. 2023. PMID: 37378433 Free PMC article.
Cannabidiol mitigates radiation-induced intestine ferroptosis via facilitating the heterodimerization of RUNX3 with CBFβ thereby promoting transactivation of GPX4.
Huang C, Liao Z, Zhang L, Shen P, Wu Z, Li G, Huang Y, Ao T, Luo L, Hu C, Wang N, Quzhuo R, Tian L, Huangfu C, Gao Y. Huang C, et al. Among authors: zhang l. Free Radic Biol Med. 2024 Jun 1:S0891-5849(24)00506-9. doi: 10.1016/j.freeradbiomed.2024.05.047. Online ahead of print. Free Radic Biol Med. 2024. PMID: 38830513
Imaging Neurotransmitters with Small-Molecule Fluorescent Probes.
Bade A, Yadav P, Zhang L, Naidu Bypaneni R, Xu M, Glass TE. Bade A, et al. Among authors: zhang l. Angew Chem Int Ed Engl. 2024 Jun 3:e202406401. doi: 10.1002/anie.202406401. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38831475
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