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Variant mutation in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation.
Kubinski HC, Despres HW, Johnson BA, Schmidt MM, Jaffrani SA, Mills MG, Lokugamage K, Dumas CM, Shirley DJ, Estes LK, Pekosz A, Crothers JW, Roychoudhury P, Greninger AL, Jerome KR, Di Genova BM, Walker DH, Ballif BA, Ladinsky MS, Bjorkman PJ, Menachery VD, Bruce EA. Kubinski HC, et al. Among authors: jerome kr. bioRxiv [Preprint]. 2024 Mar 11:2024.03.08.584120. doi: 10.1101/2024.03.08.584120. bioRxiv. 2024. PMID: 38559000 Free PMC article. Preprint.
Surveillance of Vermont wildlife in 2021-2022 reveals no detected SARS-CoV-2 viral RNA.
Despres HW, Mills MG, Schmidt MM, Gov J, Perez Y, Jindrich M, Crawford AML, Kohl WT, Rosenblatt E, Kubinski HC, Simmons BC, Nippes MC, Goldenberg AJ, Murtha KE, Nicoloro S, Harris MJ, Feeley AC, Gelinas TK, Cronin MK, Frederick RS, Thomas M, Johnson ME, Murphy J, Lenzini EB, Carr PA Jr, Berger DH, Mehta SP, Floreani CJ, Koval AC, Young AL, Fish JH, Wallace J, Chaney E, Ushay G, Ross RS, Vostal EM, Thisner MC, Gonet KE, Deane OC, Pelletiere KR, Rockafeller VC, Waterman M, Barry TW, Goering CC, Shipman SD, Shiers AC, Reilly CE, Duff AM, Shirley DJ, Jerome KR, Pérez-Osorio AC, Greninger AL, Fortin N, Mosher BA, Bruce EA. Despres HW, et al. Among authors: jerome kr. bioRxiv [Preprint]. 2023 Apr 26:2023.04.25.538264. doi: 10.1101/2023.04.25.538264. bioRxiv. 2023. PMID: 37162835 Free PMC article. Updated. Preprint.
Phylogenetic estimates of SARS-CoV-2 introductions into Washington State.
Tordoff DM, Greninger AL, Roychoudhury P, Shrestha L, Xie H, Jerome KR, Breit N, Huang ML, Famulare M, Herbeck JT. Tordoff DM, et al. Among authors: jerome kr. medRxiv [Preprint]. 2021 Apr 7:2021.04.05.21254924. doi: 10.1101/2021.04.05.21254924. medRxiv. 2021. PMID: 33855313 Free PMC article. Updated. Preprint.
An international, interlaboratory ring trial confirms the feasibility of an open-source, extraction-less "direct" RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples.
Mills MG, Bruce E, Huang ML, Crothers JW, Hyrien O, Oura CAL, Blake L, Jordan AB, Hester S, Wehmas L, Mari B, Barby P, Lacoux C, Fassy J, Vial P, Vial C, Martinez JRW, Oladipo OO, Inuwa B, Shittu I, Meseko CA, Chammas R, Santos CF, José Dionísio T, Garbieri TF, Parisi VA, Mendes-Correa MC, dePaula AV, Romano CM, Góes LGB, Minoprio P, Campos AC, Cunha MP, Vilela APP, Nyirenda T, Mkakosya RS, Muula AS, Dumm RE, Harris RM, Mitchell CA, Pettit S, Botten J, Jerome KR. Mills MG, et al. Among authors: jerome kr. medRxiv [Preprint]. 2021 Apr 16:2021.04.10.21254091. doi: 10.1101/2021.04.10.21254091. medRxiv. 2021. PMID: 33880478 Free PMC article. Updated. Preprint.
Differences in expression of tumor suppressor, innate immune, inflammasome, and potassium/gap junction channel host genes significantly predict viral reservoir size during treated HIV infection.
Dwivedi AK, Siegel DA, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Levy CN, Roychoudhury P, Hladik F, Jerome KR, Henrich TJ, Deeks SG, Lee SA. Dwivedi AK, et al. Among authors: jerome kr. bioRxiv [Preprint]. 2023 Jan 12:2023.01.10.523535. doi: 10.1101/2023.01.10.523535. bioRxiv. 2023. PMID: 36712077 Free PMC article. Preprint.
SARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
Fisher LH, Kee JJ, Liu A, Espinosa CM, Randhawa AK, Ludwig J, Magaret CA, Robinson ST, Gilbert PB, Hyrien O, Kublin JG, Rouphael N, Falsey AR, Sobieszczyk ME, El Sahly HM, Grinsztejn B, Gray GE, Kotloff KL, Gay CL, Leav B, Hirsch I, Struyf F, Dunkle LM, Neuzil KM, Corey L, Huang Y, Goepfert PA, Walsh SR, Baden LR, Janes H; COVID-19 Prevention Network (CoVPN). Fisher LH, et al. JAMA Netw Open. 2024 May 1;7(5):e2412835. doi: 10.1001/jamanetworkopen.2024.12835. JAMA Netw Open. 2024. PMID: 38780941 Free PMC article.
SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir.
Singh K, Rubenstein K, Callier V, Shaw-Saliba K, Rupert A, Dewar R, Laverdure S, Highbarger H, Lallemand P, Huang ML, Jerome KR, Sampoleo R, Mills MG, Greninger AL, Juneja K, Porter D, Benson CA, Dempsey W, El Sahly HM, Focht C, Jilg N, Paules CI, Rapaka RR, Uyeki TM, Lane HC, Beigel J, Dodd LE; Adaptive COVID-19 Treatment Trial (ACTT-1) Study Group Members. Singh K, et al. Among authors: jerome kr. J Infect Dis. 2024 Apr 24:jiae198. doi: 10.1093/infdis/jiae198. Online ahead of print. J Infect Dis. 2024. PMID: 38657001
353 results