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Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis.
Schmidt HM, DeVallance ER, Lewis SE, Wood KC, Annarapu GK, Carreño M, Hahn SA, Seman M, Maxwell BA, Hileman EA, Xu JZ, Velayutham M, Geldenhuys WJ, Vitturi DA, Shiva S, Kelley EE, Straub AC. Schmidt HM, et al. Among authors: lewis se. Redox Biol. 2023 Jun;62:102636. doi: 10.1016/j.redox.2023.102636. Epub 2023 Feb 13. Redox Biol. 2023. PMID: 36906950 Free PMC article.
Redox imbalance in COVID-19 pathophysiology.
Majumder N, Deepak V, Hadique S, Aesoph D, Velayutham M, Ye Q, Mazumder MHH, Lewis SE, Kodali V, Roohollahi A, Guo NL, Hu G, Khramtsov VV, Johnson RJ, Wen S, Kelley EE, Hussain S. Majumder N, et al. Among authors: lewis se. Redox Biol. 2022 Oct;56:102465. doi: 10.1016/j.redox.2022.102465. Epub 2022 Sep 11. Redox Biol. 2022. PMID: 36116160 Free PMC article.
Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities.
Harmon DB, Mandler WK, Sipula IJ, Dedousis N, Lewis SE, Eckels JT, Du J, Wang Y, Huckestein BR, Pagano PJ, Cifuentes-Pagano E, Homanics GE, Van't Erve TJ, Stefanovic-Racic M, Jurczak MJ, O'Doherty RM, Kelley EE. Harmon DB, et al. Among authors: lewis se. Diabetes. 2019 Jun;68(6):1221-1229. doi: 10.2337/db18-1198. Epub 2019 Apr 1. Diabetes. 2019. PMID: 30936145 Free PMC article.
Xanthine Oxidase Drives Hemolysis and Vascular Malfunction in Sickle Cell Disease.
Schmidt HM, Wood KC, Lewis SE, Hahn SA, Williams XM, McMahon B, Baust JJ, Yuan S, Bachman TN, Wang Y, Oh JY, Ghosh S, Ofori-Acquah SF, Lebensburger JD, Patel RP, Du J, Vitturi DA, Kelley EE, Straub AC. Schmidt HM, et al. Among authors: lewis se. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):769-782. doi: 10.1161/ATVBAHA.120.315081. Epub 2020 Dec 3. Arterioscler Thromb Vasc Biol. 2021. PMID: 33267657 Free PMC article.
479 results