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Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC.
Zhang H, Peyton L, McCarroll A, de León Guerrerro SD, Zhang S, Gowda P, Sirkin D, El Achwah M, Duhe A, Wood WG, Jamison B, Tracy G, Pollak R, Hart RP, Pato CN, Mulle JG, Sanders AR, Pang ZP, Duan J. Zhang H, et al. Among authors: sanders ar. bioRxiv [Preprint]. 2024 Mar 19:2024.03.18.585542. doi: 10.1101/2024.03.18.585542. bioRxiv. 2024. PMID: 38562852 Free PMC article. Preprint.
Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons.
Kozlova A, Zhang S, Kotlar AV, Jamison B, Zhang H, Shi S, Forrest MP, McDaid J, Cutler DJ, Epstein MP, Zwick ME, Pang ZP, Sanders AR, Warren ST, Gejman PV, Mulle JG, Duan J. Kozlova A, et al. Among authors: sanders ar. Am J Hum Genet. 2022 Aug 4;109(8):1500-1519. doi: 10.1016/j.ajhg.2022.07.001. Am J Hum Genet. 2022. PMID: 35931052 Free PMC article.
Modeling PTSD neuronal stress responses in a dish.
Zhang S, Sanders AR, Duan J. Zhang S, et al. Among authors: sanders ar. Nat Neurosci. 2022 Nov;25(11):1402-1404. doi: 10.1038/s41593-022-01172-9. Nat Neurosci. 2022. PMID: 36266472 Free PMC article.
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.
Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Zhang S, et al. Among authors: sanders ar. Science. 2020 Jul 31;369(6503):561-565. doi: 10.1126/science.aay3983. Science. 2020. PMID: 32732423 Free PMC article.
Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.
Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan J. Forrest MP, et al. Among authors: sanders ar. Cell Stem Cell. 2017 Sep 7;21(3):305-318.e8. doi: 10.1016/j.stem.2017.07.008. Epub 2017 Aug 10. Cell Stem Cell. 2017. PMID: 28803920 Free PMC article.
The role of genetics in the etiology of schizophrenia.
Gejman PV, Sanders AR, Duan J. Gejman PV, et al. Among authors: sanders ar. Psychiatr Clin North Am. 2010 Mar;33(1):35-66. doi: 10.1016/j.psc.2009.12.003. Psychiatr Clin North Am. 2010. PMID: 20159339 Free PMC article. Review.
176 results