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Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC.
Zhang H, Peyton L, McCarroll A, de León Guerrerro SD, Zhang S, Gowda P, Sirkin D, El Achwah M, Duhe A, Wood WG, Jamison B, Tracy G, Pollak R, Hart RP, Pato CN, Mulle JG, Sanders AR, Pang ZP, Duan J. Zhang H, et al. Among authors: zhang s. bioRxiv [Preprint]. 2024 Mar 19:2024.03.18.585542. doi: 10.1101/2024.03.18.585542. bioRxiv. 2024. PMID: 38562852 Free PMC article. Preprint.
Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons.
Kozlova A, Zhang S, Kotlar AV, Jamison B, Zhang H, Shi S, Forrest MP, McDaid J, Cutler DJ, Epstein MP, Zwick ME, Pang ZP, Sanders AR, Warren ST, Gejman PV, Mulle JG, Duan J. Kozlova A, et al. Among authors: zhang s, zhang h. Am J Hum Genet. 2022 Aug 4;109(8):1500-1519. doi: 10.1016/j.ajhg.2022.07.001. Am J Hum Genet. 2022. PMID: 35931052 Free PMC article.
Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.
Zhang S, Zhang H, Forrest MP, Zhou Y, Sun X, Bagchi VA, Kozlova A, Santos MD, Piguel NH, Dionisio LE, Sanders AR, Pang ZP, He X, Penzes P, Duan J. Zhang S, et al. Among authors: zhang h. Cell Genom. 2023 Aug 28;3(9):100399. doi: 10.1016/j.xgen.2023.100399. eCollection 2023 Sep 13. Cell Genom. 2023. PMID: 37719141 Free PMC article.
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.
Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Zhang S, et al. Among authors: zhang h. Science. 2020 Jul 31;369(6503):561-565. doi: 10.1126/science.aay3983. Science. 2020. PMID: 32732423 Free PMC article.
Modeling PTSD neuronal stress responses in a dish.
Zhang S, Sanders AR, Duan J. Zhang S, et al. Nat Neurosci. 2022 Nov;25(11):1402-1404. doi: 10.1038/s41593-022-01172-9. Nat Neurosci. 2022. PMID: 36266472 Free PMC article.
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