Shin JY - Search Results

1

mTOR Inhibition Prolongs Survival and Has Beneficial Effects on Heart Function After Onset of Lamin A/C Gene Mutation Cardiomyopathy in Mice.

Wu W, Jin Q, Östlund C, Tanji K, Shin JY, Han J, Leu CS, Kushner J, Worman HJ. Wu W, et al. Among authors: shin jy. Circ Heart Fail. 2024 Apr;17(4):e011110. doi: 10.1161/CIRCHEARTFAILURE.123.011110. Epub 2024 Apr 3. Circ Heart Fail. 2024. PMID: 38567527 Free PMC article.

2

Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation.

Wu W, Chordia MD, Hart BP, Kumarasinghe ES, Ji MK, Bhargava A, Lawlor MW, Shin JY, Sera F, Homma S, Muchir A, Khire UR, Worman HJ. Wu W, et al. Among authors: shin jy. Bioorg Med Chem. 2017 Feb 1;25(3):1004-1013. doi: 10.1016/j.bmc.2016.12.014. Epub 2016 Dec 9. Bioorg Med Chem. 2017. PMID: 28011205 Free PMC article.

3

Postnatal development of mice with combined genetic depletions of lamin A/C, emerin and lamina-associated polypeptide 1.

Wang Y, Shin JY, Nakanishi K, Homma S, Kim GJ, Tanji K, Joseph LC, Morrow JP, Stewart CL, Dauer WT, Worman HJ. Wang Y, et al. Among authors: shin jy. Hum Mol Genet. 2019 Aug 1;28(15):2486-2500. doi: 10.1093/hmg/ddz082. Hum Mol Genet. 2019. PMID: 31009944 Free PMC article.

4

A lamin A/C variant causing striated muscle disease provides insights into filament organization.

Kronenberg-Tenga R, Tatli M, Eibauer M, Wu W, Shin JY, Bonne G, Worman HJ, Medalia O. Kronenberg-Tenga R, et al. Among authors: shin jy. J Cell Sci. 2021 Mar 22;134(6):jcs256156. doi: 10.1242/jcs.256156. J Cell Sci. 2021. PMID: 33536248 Free PMC article.

5

Molecular Pathology of Laminopathies.

Shin JY, Worman HJ. Shin JY, et al. Annu Rev Pathol. 2022 Jan 24;17:159-180. doi: 10.1146/annurev-pathol-042220-034240. Epub 2021 Oct 21. Annu Rev Pathol. 2022. PMID: 34672689 Free PMC article. Review.

6

Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets.

Östlund C, Hernandez-Ono A, Turk SJ, Dauer WT, Ginsberg HN, Worman HJ, Shin JY. Östlund C, et al. Among authors: shin jy. J Lipid Res. 2022 Oct;63(10):100277. doi: 10.1016/j.jlr.2022.100277. Epub 2022 Sep 10. J Lipid Res. 2022. PMID: 36100089 Free PMC article.

7

Lamina-associated polypeptide 1: protein interactions and tissue-selective functions.

Shin JY, Dauer WT, Worman HJ. Shin JY, et al. Semin Cell Dev Biol. 2014 May;29:164-8. doi: 10.1016/j.semcdb.2014.01.010. Epub 2014 Feb 5. Semin Cell Dev Biol. 2014. PMID: 24508913 Free PMC article. Review.

8

A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder.

Wang Y, Lichter-Konecki U, Anyane-Yeboa K, Shaw JE, Lu JT, Östlund C, Shin JY, Clark LN, Gundersen GG, Nagy PL, Worman HJ. Wang Y, et al. Among authors: shin jy. J Cell Sci. 2016 May 15;129(10):1975-80. doi: 10.1242/jcs.187302. Epub 2016 Mar 31. J Cell Sci. 2016. PMID: 27034136 Free PMC article.

9

Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth.

Shin JY, Méndez-López I, Hong M, Wang Y, Tanji K, Wu W, Shugol L, Krauss RS, Dauer WT, Worman HJ. Shin JY, et al. Hum Mol Genet. 2017 Jan 1;26(1):65-78. doi: 10.1093/hmg/ddw368. Hum Mol Genet. 2017. PMID: 27798115 Free PMC article.

10

Dynamic regulation of hepatic lipid metabolism by torsinA and its activators.

Hernandez-Ono A, Zhao YP, Murray JW, Östlund C, Lee MJ, Shi A, Dauer WT, Worman HJ, Ginsberg HN, Shin JY. Hernandez-Ono A, et al. Among authors: shin jy. JCI Insight. 2024 Feb 8;9(3):e175328. doi: 10.1172/jci.insight.175328. JCI Insight. 2024. PMID: 38194265 Free PMC article.

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