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Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Walters LC, Harlos K, Brackenridge S, Rozbesky D, Barrett JR, Jain V, Walter TS, O'Callaghan CA, Borrow P, Toebes M, Hansen SG, Sacha JB, Abdulhaqq S, Greene JM, Früh K, Marshall E, Picker LJ, Jones EY, McMichael AJ, Gillespie GM. Walters LC, et al. Among authors: brackenridge s. Nat Commun. 2018 Aug 7;9(1):3137. doi: 10.1038/s41467-018-05459-z. Nat Commun. 2018. PMID: 30087334 Free PMC article.
Identification of novel HIV-1-derived HLA-E-binding peptides.
Hannoun Z, Lin Z, Brackenridge S, Kuse N, Akahoshi T, Borthwick N, McMichael A, Murakoshi H, Takiguchi M, Hanke T. Hannoun Z, et al. Among authors: brackenridge s. Immunol Lett. 2018 Oct;202:65-72. doi: 10.1016/j.imlet.2018.08.005. Epub 2018 Aug 30. Immunol Lett. 2018. PMID: 30172717 Free PMC article.
HLA-E-restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities.
Yang H, Rei M, Brackenridge S, Brenna E, Sun H, Abdulhaqq S, Liu MKP, Ma W, Kurupati P, Xu X, Cerundolo V, Jenkins E, Davis SJ, Sacha JB, Früh K, Picker LJ, Borrow P, Gillespie GM, McMichael AJ. Yang H, et al. Among authors: brackenridge s. Sci Immunol. 2021 Mar 25;6(57):eabg1703. doi: 10.1126/sciimmunol.abg1703. Sci Immunol. 2021. PMID: 33766848 Free PMC article.
HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes.
Karnaukhov V, Paes W, Woodhouse IB, Partridge T, Nicastri A, Brackenridge S, Shcherbinin D, Chudakov DM, Zvyagin IV, Ternette N, Koohy H, Borrow P, Shugay M. Karnaukhov V, et al. Among authors: brackenridge s. Front Immunol. 2022 Dec 20;13:1067463. doi: 10.3389/fimmu.2022.1067463. eCollection 2022. Front Immunol. 2022. PMID: 36605212 Free PMC article.
Intracellular trafficking of HLA-E and its regulation.
He W, Gea-Mallorquí E, Colin-York H, Fritzsche M, Gillespie GM, Brackenridge S, Borrow P, McMichael AJ. He W, et al. Among authors: brackenridge s. J Exp Med. 2023 Aug 7;220(8):e20221941. doi: 10.1084/jem.20221941. Epub 2023 May 4. J Exp Med. 2023. PMID: 37140910 Free PMC article.
Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.
Hansen SG, Wu HL, Burwitz BJ, Hughes CM, Hammond KB, Ventura AB, Reed JS, Gilbride RM, Ainslie E, Morrow DW, Ford JC, Selseth AN, Pathak R, Malouli D, Legasse AW, Axthelm MK, Nelson JA, Gillespie GM, Walters LC, Brackenridge S, Sharpe HR, López CA, Früh K, Korber BT, McMichael AJ, Gnanakaran S, Sacha JB, Picker LJ. Hansen SG, et al. Among authors: brackenridge s. Science. 2016 Feb 12;351(6274):714-20. doi: 10.1126/science.aac9475. Epub 2016 Jan 21. Science. 2016. PMID: 26797147 Free PMC article.
The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques.
Wu HL, Wiseman RW, Hughes CM, Webb GM, Abdulhaqq SA, Bimber BN, Hammond KB, Reed JS, Gao L, Burwitz BJ, Greene JM, Ferrer F, Legasse AW, Axthelm MK, Park BS, Brackenridge S, Maness NJ, McMichael AJ, Picker LJ, O'Connor DH, Hansen SG, Sacha JB. Wu HL, et al. Among authors: brackenridge s. J Immunol. 2018 Jan 1;200(1):49-60. doi: 10.4049/jimmunol.1700841. Epub 2017 Nov 17. J Immunol. 2018. PMID: 29150562 Free PMC article.
Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Walters LC, Harlos K, Brackenridge S, Rozbesky D, Barrett JR, Jain V, Walter TS, O'Callaghan CA, Borrow P, Toebes M, Hansen SG, Sacha JB, Abdulhaqq S, Greene JM, Früh K, Marshall E, Picker LJ, Jones EY, McMichael AJ, Gillespie GM. Walters LC, et al. Among authors: brackenridge s. Nat Commun. 2018 Nov 13;9(1):4833. doi: 10.1038/s41467-018-07304-9. Nat Commun. 2018. PMID: 30420666 Free PMC article.
Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection.
Paes W, Leonov G, Partridge T, Chikata T, Murakoshi H, Frangou A, Brackenridge S, Nicastri A, Smith AG, Learn GH, Li Y, Parker R, Oka S, Pellegrino P, Williams I, Haynes BF, McMichael AJ, Shaw GM, Hahn BH, Takiguchi M, Ternette N, Borrow P. Paes W, et al. Among authors: brackenridge s. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24748-24759. doi: 10.1073/pnas.1911622116. Epub 2019 Nov 20. Proc Natl Acad Sci U S A. 2019. PMID: 31748275 Free PMC article.
32 results