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Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages.
Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong MN, Kylies D, Gräfe SK, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm AB, Richardt U, Eggert P, Tappe D, Weidemann SA, Ghosh S, Krebs CF, A-Gonzalez N, Worthmann A, Lohse AW, Huber S, Rothlin CV, Puelles VG, Jacobs T, Gagliani N, Bosurgi L. Liebold I, et al. Among authors: lohse aw. Science. 2024 Apr 5;384(6691):eabo7027. doi: 10.1126/science.abo7027. Epub 2024 Apr 5. Science. 2024. PMID: 38574142
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients.
Zhao Y, Kilian C, Turner JE, Bosurgi L, Roedl K, Bartsch P, Gnirck AC, Cortesi F, Schultheiß C, Hellmig M, Enk LUB, Hausmann F, Borchers A, Wong MN, Paust HJ, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur-Wiesch JS, Puelles VG, Sperhake JP, Addo MM, Lohse AW, Binder M, Huber S, Huber TB, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs CF. Zhao Y, et al. Among authors: lohse aw. Sci Immunol. 2021 Feb 23;6(56):eabf6692. doi: 10.1126/sciimmunol.abf6692. Sci Immunol. 2021. PMID: 33622974 Free PMC article.
A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease.
Pelczar P, Witkowski M, Perez LG, Kempski J, Hammel AG, Brockmann L, Kleinschmidt D, Wende S, Haueis C, Bedke T, Witkowski M, Krasemann S, Steurer S, Booth CJ, Busch P, König A, Rauch U, Benten D, Izbicki JR, Rösch T, Lohse AW, Strowig T, Gagliani N, Flavell RA, Huber S. Pelczar P, et al. Among authors: lohse aw. Science. 2016 Oct 21;354(6310):358-362. doi: 10.1126/science.aah5903. Science. 2016. PMID: 27846573
Molecular and functional heterogeneity of IL-10-producing CD4+ T cells.
Brockmann L, Soukou S, Steglich B, Czarnewski P, Zhao L, Wende S, Bedke T, Ergen C, Manthey C, Agalioti T, Geffken M, Seiz O, Parigi SM, Sorini C, Geginat J, Fujio K, Jacobs T, Roesch T, Izbicki JR, Lohse AW, Flavell RA, Krebs C, Gustafsson JA, Antonson P, Roncarolo MG, Villablanca EJ, Gagliani N, Huber S. Brockmann L, et al. Among authors: lohse aw. Nat Commun. 2018 Dec 21;9(1):5457. doi: 10.1038/s41467-018-07581-4. Nat Commun. 2018. PMID: 30575716 Free PMC article.
Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis.
Poch T, Krause J, Casar C, Liwinski T, Glau L, Kaufmann M, Ahrenstorf AE, Hess LU, Ziegler AE, Martrus G, Lunemann S, Sebode M, Li J, Schwinge D, Krebs CF, Franke A, Friese MA, Oldhafer KJ, Fischer L, Altfeld M, Lohse AW, Huber S, Tolosa E, Gagliani N, Schramm C. Poch T, et al. Among authors: lohse aw. J Hepatol. 2021 Aug;75(2):414-423. doi: 10.1016/j.jhep.2021.03.016. Epub 2021 Mar 24. J Hepatol. 2021. PMID: 33774059 Free PMC article.
Variant syndromes of primary biliary cholangitis.
Schulz L, Sebode M, Weidemann SA, Lohse AW. Schulz L, et al. Among authors: lohse aw. Best Pract Res Clin Gastroenterol. 2018 Jun-Aug;34-35:55-61. doi: 10.1016/j.bpg.2018.06.003. Epub 2018 Jun 14. Best Pract Res Clin Gastroenterol. 2018. PMID: 30343711 Review.
Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype.
Krause J, von Felden J, Casar C, Fründt TW, Galaski J, Schmidt C, Jung C, Ittrich H, Weidemann SA, Krech T, Heumann A, Li J, Fischer L, Sauter G, Lohse AW, Wege H, Schulze K. Krause J, et al. Among authors: lohse aw. BMC Cancer. 2020 Nov 23;20(1):1130. doi: 10.1186/s12885-020-07580-z. BMC Cancer. 2020. PMID: 33225916 Free PMC article.
Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis.
Glaser F, John C, Engel B, Höh B, Weidemann S, Dieckhoff J, Stein S, Becker N, Casar C, Schuran FA, Wieschendorf B, Preti M, Jessen F, Franke A, Carambia A, Lohse AW, Ittrich H, Herkel J, Heeren J, Schramm C, Schwinge D. Glaser F, et al. Among authors: lohse aw. J Hepatol. 2019 Oct;71(4):783-792. doi: 10.1016/j.jhep.2019.05.030. Epub 2019 Jun 14. J Hepatol. 2019. PMID: 31207266
Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis.
Müller AL, Casar C, Preti M, Krzikalla D, Gottwick C, Averhoff P, Rosenstiel P, Gelderblom M, Altfeld M, Lohse AW, Steinmann S, Sebode M, Krause J, Schwinge D, Schramm C, Carambia A, Herkel J. Müller AL, et al. Among authors: lohse aw. J Hepatol. 2022 Dec;77(6):1532-1544. doi: 10.1016/j.jhep.2022.06.025. Epub 2022 Jul 5. J Hepatol. 2022. PMID: 35798133 Free article.
587 results