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Post-transcriptional splicing can occur in a slow-moving zone around the gene.
Coté A, O'Farrell A, Dardani I, Dunagin M, Coté C, Wan Y, Bayatpour S, Drexler HL, Alexander KA, Chen F, Wassie AT, Patel R, Pham K, Boyden ES, Berger S, Phillips-Cremins J, Churchman LS, Raj A. Coté A, et al. Among authors: dunagin m. Elife. 2024 Apr 5;12:RP91357. doi: 10.7554/eLife.91357. Elife. 2024. PMID: 38577979 Free PMC article.
ClampFISH detects individual nucleic acid molecules using click chemistry-based amplification.
Rouhanifard SH, Mellis IA, Dunagin M, Bayatpour S, Jiang CL, Dardani I, Symmons O, Emert B, Torre E, Cote A, Sullivan A, Stamatoyannopoulos JA, Raj A. Rouhanifard SH, et al. Among authors: dunagin m. Nat Biotechnol. 2018 Nov 12:10.1038/nbt.4286. doi: 10.1038/nbt.4286. Online ahead of print. Nat Biotechnol. 2018. PMID: 30418432 Free PMC article.
p53 mediates target gene association with nuclear speckles for amplified RNA expression.
Alexander KA, Coté A, Nguyen SC, Zhang L, Gholamalamdari O, Agudelo-Garcia P, Lin-Shiao E, Tanim KMA, Lim J, Biddle N, Dunagin MC, Good CR, Mendoza MR, Little SC, Belmont A, Joyce EF, Raj A, Berger SL. Alexander KA, et al. Among authors: dunagin mc. Mol Cell. 2021 Apr 15;81(8):1666-1681.e6. doi: 10.1016/j.molcel.2021.03.006. Epub 2021 Apr 5. Mol Cell. 2021. PMID: 33823140 Free PMC article.
LADL: light-activated dynamic looping for endogenous gene expression control.
Kim JH, Rege M, Valeri J, Dunagin MC, Metzger A, Titus KR, Gilgenast TG, Gong W, Beagan JA, Raj A, Phillips-Cremins JE. Kim JH, et al. Among authors: dunagin mc. Nat Methods. 2019 Jul;16(7):633-639. doi: 10.1038/s41592-019-0436-5. Epub 2019 Jun 24. Nat Methods. 2019. PMID: 31235883 Free PMC article.
CTCF blocks antisense transcription initiation at divergent promoters.
Luan J, Vermunt MW, Syrett CM, Coté A, Tome JM, Zhang H, Huang A, Luppino JM, Keller CA, Giardine BM, Zhang S, Dunagin MC, Zhang Z, Joyce EF, Lis JT, Raj A, Hardison RC, Blobel GA. Luan J, et al. Among authors: dunagin mc. Nat Struct Mol Biol. 2022 Nov;29(11):1136-1144. doi: 10.1038/s41594-022-00855-y. Epub 2022 Nov 11. Nat Struct Mol Biol. 2022. PMID: 36369346 Free PMC article.
24 results