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AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.
Grigoryan L, Feng Y, Bellusci L, Lai L, Wali B, Ellis M, Yuan M, Arunachalam PS, Hu M, Kowli S, Gupta S, Maysel-Auslender S, Maecker HT, Samaha H, Rouphael N, Wilson IA, Moreno AC, Suthar MS, Khurana S, Pillet S, Charland N, Ward BJ, Pulendran B. Grigoryan L, et al. Among authors: ward bj. Sci Immunol. 2024 Apr 5;9(94):eadi8039. doi: 10.1126/sciimmunol.adi8039. Epub 2024 Apr 5. Sci Immunol. 2024. PMID: 38579013
Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates.
Pillet S, Arunachalam PS, Andreani G, Golden N, Fontenot J, Aye PP, Röltgen K, Lehmicke G, Gobeil P, Dubé C, Trépanier S, Charland N, D'Aoust MA, Russell-Lodrigue K, Monjure C, Blair RV, Boyd SD, Bohm RP, Rappaport J, Villinger F, Landry N, Pulendran B, Ward BJ. Pillet S, et al. Among authors: ward bj. Cell Mol Immunol. 2022 Feb;19(2):222-233. doi: 10.1038/s41423-021-00809-2. Epub 2022 Jan 5. Cell Mol Immunol. 2022. PMID: 34983950 Free PMC article.
A Single Intramuscular Dose of a Plant-Made Virus-Like Particle Vaccine Elicits a Balanced Humoral and Cellular Response and Protects Young and Aged Mice from Influenza H1N1 Virus Challenge despite a Modest/Absent Humoral Response.
Hodgins B, Yam KK, Winter K, Pillet S, Landry N, Ward BJ. Hodgins B, et al. Among authors: ward bj. Clin Vaccine Immunol. 2017 Dec 5;24(12):e00273-17. doi: 10.1128/CVI.00273-17. Print 2017 Dec. Clin Vaccine Immunol. 2017. PMID: 29021303 Free PMC article.
Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages.
Makarkov AI, Golizeh M, Ruiz-Lancheros E, Gopal AA, Costas-Cancelas IN, Chierzi S, Pillet S, Charland N, Landry N, Rouiller I, Wiseman PW, Ndao M, Ward BJ. Makarkov AI, et al. Among authors: ward bj. NPJ Vaccines. 2019 May 15;4:17. doi: 10.1038/s41541-019-0111-y. eCollection 2019. NPJ Vaccines. 2019. PMID: 31123605 Free PMC article.
285 results