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Page 1
Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial.
Yarchoan M, Gane EJ, Marron TU, Perales-Linares R, Yan J, Cooch N, Shu DH, Fertig EJ, Kagohara LT, Bartha G, Northcott J, Lyle J, Rochestie S, Peters J, Connor JT, Jaffee EM, Csiki I, Weiner DB, Perales-Puchalt A, Sardesai NY. Yarchoan M, et al. Among authors: perales puchalt a. Nat Med. 2024 Apr;30(4):1044-1053. doi: 10.1038/s41591-024-02894-y. Epub 2024 Apr 7. Nat Med. 2024. PMID: 38584166 Free PMC article. Clinical Trial.
Teclistamab impairs humoral immunity in patients with heavily pretreated myeloma: importance of immunoglobulin supplementation.
Frerichs KA, Verkleij CPM, Mateos MV, Martin TG, Rodriguez C, Nooka A, Banerjee A, Chastain K, Perales-Puchalt A, Stephenson T, Uhlar C, Kobos R, van der Holt B, Kruyswijk S, Kuipers MT, Groen K, Vishwamitra D, Skerget S, Cortes-Selva D, Doyle M, Zaaijer HL, Zweegman S, Verona RI, van de Donk NWCJ. Frerichs KA, et al. Among authors: perales puchalt a. Blood Adv. 2024 Jan 9;8(1):194-206. doi: 10.1182/bloodadvances.2023011658. Blood Adv. 2024. PMID: 38052042 Free PMC article.
Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers.
Bordoloi D, Kulkarni AJ, Adeniji OS, Pampena MB, Bhojnagarwala PS, Zhao S, Ionescu C, Perales-Puchalt A, Parzych EM, Zhu X, Ali AR, Cassel J, Zhang R, Betts MR, Abdel-Mohsen M, Weiner DB. Bordoloi D, et al. Among authors: perales puchalt a. Sci Adv. 2023 Nov 3;9(44):eadh4379. doi: 10.1126/sciadv.adh4379. Epub 2023 Nov 1. Sci Adv. 2023. PMID: 37910620 Free PMC article.
Multivalent in vivo delivery of DNA-encoded bispecific T cell engagers effectively controls heterogeneous GBM tumors and mitigates immune escape.
Park DH, Liaw K, Bhojnagarwala P, Zhu X, Choi J, Ali AR, Bordoloi D, Gary EN, O'Connell RP, Kulkarni A, Guimet D, Smith T, Perales-Puchalt A, Patel A, Weiner DB. Park DH, et al. Among authors: perales puchalt a. Mol Ther Oncolytics. 2023 Feb 16;28:249-263. doi: 10.1016/j.omto.2023.02.004. eCollection 2023 Mar 16. Mol Ther Oncolytics. 2023. PMID: 36915911 Free PMC article.
DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas.
Zhu X, Perales-Puchalt A, Wojtak K, Xu Z, Yun K, Bhojnagarwala PS, Bordoloi D, Park DH, Liaw K, Bah MA, Lieberman PM, Gary EN, Patel A, Weiner DB. Zhu X, et al. Among authors: perales puchalt a. Mol Ther Oncolytics. 2021 Dec 21;24:218-229. doi: 10.1016/j.omto.2021.12.017. eCollection 2022 Mar 17. Mol Ther Oncolytics. 2021. PMID: 35071745 Free PMC article.
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells.
Payne KK, Mine JA, Biswas S, Chaurio RA, Perales-Puchalt A, Anadon CM, Costich TL, Harro CM, Walrath J, Ming Q, Tcyganov E, Buras AL, Rigolizzo KE, Mandal G, Lajoie J, Ophir M, Tchou J, Marchion D, Luca VC, Bobrowicz P, McLaughlin B, Eskiocak U, Schmidt M, Cubillos-Ruiz JR, Rodriguez PC, Gabrilovich DI, Conejo-Garcia JR. Payne KK, et al. Among authors: perales puchalt a. Science. 2020 Aug 21;369(6506):942-949. doi: 10.1126/science.aay2767. Science. 2020. PMID: 32820120 Free PMC article.
Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo.
Khoshnejad M, Perales-Puchalt A, Dia Y, Xiao P, Patel A, Xu Z, Zhu X, Yun K, Baboo I, Qureshi R, Humeau L, Muthumani K, Weiner DB. Khoshnejad M, et al. Among authors: perales puchalt a. Mol Ther Methods Clin Dev. 2020 Jun 1;18:652-663. doi: 10.1016/j.omtm.2020.05.025. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32802913 Free PMC article.
54 results