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Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.
Chandrasekaran V, Wellens S, Bourguignon A, Djidrovski I, Fransen L, Ghosh S, Mazidi Z, Murphy C, Nunes C, Singh P, Zana M, Armstrong L, Dinnyés A, Grillari J, Grillari-Voglauer R, Leonard MO, Verfaillie C, Wilmes A, Zurich MG, Exner T, Jennings P, Culot M. Chandrasekaran V, et al. Among authors: djidrovski i. Toxicol In Vitro. 2024 Apr 12;98:105826. doi: 10.1016/j.tiv.2024.105826. Online ahead of print. Toxicol In Vitro. 2024. PMID: 38615723 Free article.
Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air-liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells.
Djidrovski I, Georgiou M, Tasinato E, Leonard MO, Van den Bor J, Lako M, Armstrong L. Djidrovski I, et al. Cell Biol Toxicol. 2023 Feb;39(1):1-18. doi: 10.1007/s10565-022-09726-0. Epub 2022 May 31. Cell Biol Toxicol. 2023. PMID: 35641671 Free PMC article.
SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells.
Djidrovski I, Georgiou M, Hughes GL, Patterson EI, Casas-Sanchez A, Pennington SH, Biagini GA, Moya-Molina M, van den Bor J, Smit MJ, Chung G, Lako M, Armstrong L. Djidrovski I, et al. Stem Cells. 2021 Oct;39(10):1310-1321. doi: 10.1002/stem.3422. Epub 2021 Jun 21. Stem Cells. 2021. PMID: 34152044 Free PMC article.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface.
Collin J, Queen R, Zerti D, Dorgau B, Georgiou M, Djidrovski I, Hussain R, Coxhead JM, Joseph A, Rooney P, Lisgo S, Figueiredo F, Armstrong L, Lako M. Collin J, et al. Among authors: djidrovski i. Ocul Surf. 2021 Jan;19:190-200. doi: 10.1016/j.jtos.2020.05.013. Epub 2020 Jun 3. Ocul Surf. 2021. PMID: 32502616 Free PMC article.