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A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.
Nguyen BV, Özden C, Dong K, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankura S, Abromson NL, Tomchick DR, Chen J, Garman SC, Stratton MM. Nguyen BV, et al. Among authors: garman sc. bioRxiv [Preprint]. 2024 Mar 27:2024.03.24.586494. doi: 10.1101/2024.03.24.586494. bioRxiv. 2024. PMID: 38585726 Free PMC article. Preprint.
CaMKII binds both substrates and activators at the active site.
Özden C, Sloutsky R, Mitsugi T, Santos N, Agnello E, Gaubitz C, Foster J, Lapinskas E, Esposito EA, Saneyoshi T, Kelch BA, Garman SC, Hayashi Y, Stratton MM. Özden C, et al. Among authors: garman sc. Cell Rep. 2022 Jul 12;40(2):111064. doi: 10.1016/j.celrep.2022.111064. Cell Rep. 2022. PMID: 35830796 Free PMC article.
Characterization of CaMKIIα holoenzyme stability.
Torres-Ocampo AP, Özden C, Hommer A, Gardella A, Lapinskas E, Samkutty A, Esposito E, Garman SC, Stratton MM. Torres-Ocampo AP, et al. Among authors: garman sc. Protein Sci. 2020 Jun;29(6):1524-1534. doi: 10.1002/pro.3869. Epub 2020 May 2. Protein Sci. 2020. PMID: 32282091 Free PMC article.
Phenotypic characteristics of the p.Asn215Ser (p.N215S) GLA mutation in male and female patients with Fabry disease: A multicenter Fabry Registry study.
Germain DP, Brand E, Burlina A, Cecchi F, Garman SC, Kempf J, Laney DA, Linhart A, Maródi L, Nicholls K, Ortiz A, Pieruzzi F, Shankar SP, Waldek S, Wanner C, Jovanovic A. Germain DP, et al. Among authors: garman sc. Mol Genet Genomic Med. 2018 Apr 12;6(4):492-503. doi: 10.1002/mgg3.389. Online ahead of print. Mol Genet Genomic Med. 2018. PMID: 29649853 Free PMC article.
Ligand-promoted protein folding by biased kinetic partitioning.
Hingorani KS, Metcalf MC, Deming DT, Garman SC, Powers ET, Gierasch LM. Hingorani KS, et al. Among authors: garman sc. Nat Chem Biol. 2017 Apr;13(4):369-371. doi: 10.1038/nchembio.2303. Epub 2017 Feb 20. Nat Chem Biol. 2017. PMID: 28218913 Free PMC article.
The alpha-galactosidase A p.Arg118Cys variant does not cause a Fabry disease phenotype: data from individual patients and family studies.
Ferreira S, Ortiz A, Germain DP, Viana-Baptista M, Caldeira-Gomes A, Camprecios M, Fenollar-Cortés M, Gallegos-Villalobos Á, Garcia D, García-Robles JA, Egido J, Gutiérrez-Rivas E, Herrero JA, Mas S, Oancea R, Péres P, Salazar-Martín LM, Solera-Garcia J, Alves H, Garman SC, Oliveira JP. Ferreira S, et al. Among authors: garman sc. Mol Genet Metab. 2015 Feb;114(2):248-58. doi: 10.1016/j.ymgme.2014.11.004. Epub 2014 Nov 9. Mol Genet Metab. 2015. PMID: 25468652 Free PMC article.
39 results