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The estrogen signaling pathway reprograms prostate cancer cell metabolism and supports proliferation and disease progression.
Lafront C, Germain L, Campolina-Silva GH, Weidmann C, Berthiaume L, Hovington H, Brisson H, Jobin C, Frégeau-Proulx L, Cotau R, Gonthier K, Lacouture A, Caron P, Ménard C, Atallah C, Riopel J, Latulippe É, Bergeron A, Toren P, Guillemette C, Pelletier M, Fradet Y, Belleannée C, Pouliot F, Lacombe L, Lévesque É, Audet-Walsh É. Lafront C, et al. Among authors: guillemette c. J Clin Invest. 2024 Apr 16:e170809. doi: 10.1172/JCI170809. Online ahead of print. J Clin Invest. 2024. PMID: 38625747 Free article.
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression.
Lévesque E, Labriet A, Hovington H, Allain ÉP, Melo-Garcia L, Rouleau M, Brisson H, Turcotte V, Caron P, Villeneuve L, Leclercq M, Droit A, Audet-Walsh E, Simonyan D, Fradet Y, Lacombe L, Guillemette C. Lévesque E, et al. Among authors: guillemette c. Br J Cancer. 2020 Mar;122(7):1068-1076. doi: 10.1038/s41416-020-0749-2. Epub 2020 Feb 12. Br J Cancer. 2020. PMID: 32047296 Free PMC article.
KLF5 and NFYA factors as novel regulators of prostate cancer cell metabolism.
Poluri RTK, Paquette V, Allain ÉP, Lafront C, Joly-Beauparlant C, Weidmann C, Droit A, Guillemette C, Pelletier M, Audet-Walsh É. Poluri RTK, et al. Among authors: guillemette c. Endocr Relat Cancer. 2021 Apr;28(4):257-271. doi: 10.1530/ERC-20-0504. Endocr Relat Cancer. 2021. PMID: 33690159
Deletions of the androgen-metabolizing UGT2B genes have an effect on circulating steroid levels and biochemical recurrence after radical prostatectomy in localized prostate cancer.
Nadeau G, Bellemare J, Audet-Walsh É, Flageole C, Huang SP, Bao BY, Douville P, Caron P, Fradet Y, Lacombe L, Guillemette C, Lévesque E. Nadeau G, et al. Among authors: guillemette c. J Clin Endocrinol Metab. 2011 Sep;96(9):E1550-7. doi: 10.1210/jc.2011-1049. Epub 2011 Jul 6. J Clin Endocrinol Metab. 2011. PMID: 21733997
199 results