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Preclinical evaluation and first-in-dog clinical trials of PBMC-expanded natural killer cells for adoptive immunotherapy in dogs with cancer.
Razmara AM, Farley LE, Harris RM, Judge SJ, Lammers M, Iranpur KR, Johnson EG, Dunai C, Murphy WJ, Brown CT, Rebhun RB, Kent MS, Canter RJ. Razmara AM, et al. Among authors: murphy wj. J Immunother Cancer. 2024 Apr 16;12(4):e007963. doi: 10.1136/jitc-2023-007963. J Immunother Cancer. 2024. PMID: 38631708 Free PMC article.
Natural killer cell immunotherapy to target stem-like tumor cells.
Grossenbacher SK, Canter RJ, Murphy WJ. Grossenbacher SK, et al. Among authors: murphy wj. J Immunother Cancer. 2016 Apr 19;4:19. doi: 10.1186/s40425-016-0124-2. eCollection 2016. J Immunother Cancer. 2016. PMID: 27096096 Free PMC article.
Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy.
Luna JI, Grossenbacher SK, Murphy WJ, Canter RJ. Luna JI, et al. Among authors: murphy wj. Expert Opin Biol Ther. 2017 Mar;17(3):313-324. doi: 10.1080/14712598.2017.1271874. Epub 2016 Dec 23. Expert Opin Biol Ther. 2017. PMID: 27960589 Free PMC article. Review.
Canine cancer immunotherapy studies: linking mouse and human.
Park JS, Withers SS, Modiano JF, Kent MS, Chen M, Luna JI, Culp WTN, Sparger EE, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. Park JS, et al. Among authors: murphy wj. J Immunother Cancer. 2016 Dec 20;4:97. doi: 10.1186/s40425-016-0200-7. eCollection 2016. J Immunother Cancer. 2016. PMID: 28031824 Free PMC article. Review.
Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial.
Canter RJ, Grossenbacher SK, Foltz JA, Sturgill IR, Park JS, Luna JI, Kent MS, Culp WTN, Chen M, Modiano JF, Monjazeb AM, Lee DA, Murphy WJ. Canter RJ, et al. Among authors: murphy wj. J Immunother Cancer. 2017 Dec 19;5(1):98. doi: 10.1186/s40425-017-0305-7. J Immunother Cancer. 2017. PMID: 29254507 Free PMC article. Clinical Trial.
Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.
Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ. Judge SJ, et al. Among authors: murphy wj. PLoS One. 2020 Feb 21;15(2):e0224775. doi: 10.1371/journal.pone.0224775. eCollection 2020. PLoS One. 2020. PMID: 32084139 Free PMC article. Clinical Trial.
Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas.
Judge SJ, Darrow MA, Thorpe SW, Gingrich AA, O'Donnell EF, Bellini AR, Sturgill IR, Vick LV, Dunai C, Stoffel KM, Lyu Y, Chen S, Cho M, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. Judge SJ, et al. Among authors: murphy wj. J Immunother Cancer. 2020 Nov;8(2):e001355. doi: 10.1136/jitc-2020-001355. J Immunother Cancer. 2020. PMID: 33158916 Free PMC article.
Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target.
Gingrich AA, Reiter TE, Judge SJ, York D, Yanagisawa M, Razmara A, Sturgill I, Basmaci UN, Brady RV, Stoffel K, Murphy WJ, Rebhun RB, Brown CT, Canter RJ. Gingrich AA, et al. Among authors: murphy wj. Front Immunol. 2021 Sep 14;12:670309. doi: 10.3389/fimmu.2021.670309. eCollection 2021. Front Immunol. 2021. PMID: 34594320 Free PMC article.
Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response.
Rebhun RB, York D, Cruz SM, Judge SJ, Razmara AM, Farley LE, Brady RV, Johnson EG, Burton JH, Willcox J, Wittenburg LA, Woolard K, Dunai C, Stewart SL, Sparger EE, Withers SS, Gingrich AA, Skorupski KA, Al-Nadaf S, LeJeune AT, Culp WT, Murphy WJ, Kent MS, Canter RJ. Rebhun RB, et al. Among authors: murphy wj. J Immunother Cancer. 2022 Jun;10(6):e004493. doi: 10.1136/jitc-2022-004493. J Immunother Cancer. 2022. PMID: 35680383 Free PMC article. Clinical Trial.
609 results