Xu J - Search Results

1

Stepwise activation of a metabotropic glutamate receptor.

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Krishna Kumar K, et al. Among authors: xu j. Nature. 2024 May;629(8013):951-956. doi: 10.1038/s41586-024-07327-x. Epub 2024 Apr 17. Nature. 2024. PMID: 38632403

2

Structure-based discovery of selective positive allosteric modulators of antagonists for the M₂ muscarinic acetylcholine receptor.

Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, Christopoulos A, Shoichet BK, Sunahara RK. Korczynska M, et al. Among authors: xu j. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2419-E2428. doi: 10.1073/pnas.1718037115. Epub 2018 Feb 16. Proc Natl Acad Sci U S A. 2018. PMID: 29453275 Free PMC article.

3

Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy.

Xu J, Hu Y, Kaindl J, Risel P, Hübner H, Maeda S, Niu X, Li H, Gmeiner P, Jin C, Kobilka BK. Xu J, et al. Mol Cell. 2019 Jul 11;75(1):53-65.e7. doi: 10.1016/j.molcel.2019.04.028. Epub 2019 May 15. Mol Cell. 2019. PMID: 31103421 Free article.

4

Activation of the α_2B adrenoceptor by the sedative sympatholytic dexmedetomidine.

Yuan D, Liu Z, Kaindl J, Maeda S, Zhao J, Sun X, Xu J, Gmeiner P, Wang HW, Kobilka BK. Yuan D, et al. Among authors: xu j. Nat Chem Biol. 2020 May;16(5):507-512. doi: 10.1038/s41589-020-0492-2. Epub 2020 Mar 9. Nat Chem Biol. 2020. PMID: 32152538

5

Structure and selectivity engineering of the M₁ muscarinic receptor toxin complex.

Maeda S, Xu J, N Kadji FM, Clark MJ, Zhao J, Tsutsumi N, Aoki J, Sunahara RK, Inoue A, Garcia KC, Kobilka BK. Maeda S, et al. Among authors: xu j. Science. 2020 Jul 10;369(6500):161-167. doi: 10.1126/science.aax2517. Science. 2020. PMID: 32646996 Free PMC article.

6

Analysis of β₂AR-G_s and β₂AR-G_i complex formation by NMR spectroscopy.

Ma X, Hu Y, Batebi H, Heng J, Xu J, Liu X, Niu X, Li H, Hildebrand PW, Jin C, Kobilka BK. Ma X, et al. Among authors: xu j. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23096-23105. doi: 10.1073/pnas.2009786117. Epub 2020 Aug 31. Proc Natl Acad Sci U S A. 2020. PMID: 32868434 Free PMC article.

7

Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.

Chen G, Xu J, Inoue A, Schmidt MF, Bai C, Lu Q, Gmeiner P, Liu Z, Du Y. Chen G, et al. Among authors: xu j. Nat Commun. 2022 May 2;13(1):2375. doi: 10.1038/s41467-022-30081-5. Nat Commun. 2022. PMID: 35501348 Free PMC article.

8

Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.

Xu J, Wang Q, Hübner H, Hu Y, Niu X, Wang H, Maeda S, Inoue A, Tao Y, Gmeiner P, Du Y, Jin C, Kobilka BK. Xu J, et al. Nat Commun. 2023 Jan 23;14(1):376. doi: 10.1038/s41467-022-35726-z. Nat Commun. 2023. PMID: 36690613 Free PMC article.

9

Step-wise activation of a Family C GPCR.

Kumar KK, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Kumar KK, et al. Among authors: xu j. bioRxiv [Preprint]. 2023 Aug 30:2023.08.29.555158. doi: 10.1101/2023.08.29.555158. bioRxiv. 2023. PMID: 37693614 Free PMC article. Preprint.

10

Author Correction: Stepwise activation of a metabotropic glutamate receptor.

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Krishna Kumar K, et al. Among authors: xu j. Nature. 2024 May;629(8013):E13. doi: 10.1038/s41586-024-07470-5. Nature. 2024. PMID: 38702522 No abstract available.

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