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Dual roles of PARP-1 promote cancer growth and progression.
Schiewer MJ, Goodwin JF, Han S, Brenner JC, Augello MA, Dean JL, Liu F, Planck JL, Ravindranathan P, Chinnaiyan AM, McCue P, Gomella LG, Raj GV, Dicker AP, Brody JR, Pascal JM, Centenera MM, Butler LM, Tilley WD, Feng FY, Knudsen KE. Schiewer MJ, et al. Cancer Discov. 2012 Dec;2(12):1134-49. doi: 10.1158/2159-8290.CD-12-0120. Epub 2012 Sep 19. Cancer Discov. 2012. PMID: 22993403 Free PMC article.
Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.
Steffen JD, Tholey RM, Langelier MF, Planck JL, Schiewer MJ, Lal S, Bildzukewicz NA, Yeo CJ, Knudsen KE, Brody JR, Pascal JM. Steffen JD, et al. Among authors: schiewer mj. Cancer Res. 2014 Jan 1;74(1):31-7. doi: 10.1158/0008-5472.CAN-13-1701. Epub 2013 Nov 4. Cancer Res. 2014. PMID: 24189460 Free PMC article.
USP22 regulates oncogenic signaling pathways to drive lethal cancer progression.
Schrecengost RS, Dean JL, Goodwin JF, Schiewer MJ, Urban MW, Stanek TJ, Sussman RT, Hicks JL, Birbe RC, Draganova-Tacheva RA, Visakorpi T, DeMarzo AM, McMahon SB, Knudsen KE. Schrecengost RS, et al. Among authors: schiewer mj. Cancer Res. 2014 Jan 1;74(1):272-86. doi: 10.1158/0008-5472.CAN-13-1954. Epub 2013 Nov 6. Cancer Res. 2014. PMID: 24197134 Free PMC article.
PARP Inhibitors in Prostate Cancer.
Ramakrishnan Geethakumari P, Schiewer MJ, Knudsen KE, Kelly WK. Ramakrishnan Geethakumari P, et al. Among authors: schiewer mj. Curr Treat Options Oncol. 2017 Jun;18(6):37. doi: 10.1007/s11864-017-0480-2. Curr Treat Options Oncol. 2017. PMID: 28540598 Review.
Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors.
Chand SN, Zarei M, Schiewer MJ, Kamath AR, Romeo C, Lal S, Cozzitorto JA, Nevler A, Scolaro L, Londin E, Jiang W, Meisner-Kober N, Pishvaian MJ, Knudsen KE, Yeo CJ, Pascal JM, Winter JM, Brody JR. Chand SN, et al. Among authors: schiewer mj. Cancer Res. 2017 Sep 15;77(18):5011-5025. doi: 10.1158/0008-5472.CAN-16-2704. Epub 2017 Jul 7. Cancer Res. 2017. PMID: 28687616 Free PMC article.
Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies.
Dylgjeri E, McNair C, Goodwin JF, Raymon HK, McCue PA, Shafi AA, Leiby BE, de Leeuw R, Kothari V, McCann JJ, Mandigo AC, Chand SN, Schiewer MJ, Brand LJ, Vasilevskaya I, Gordon N, Laufer TS, Gomella LG, Lallas CD, Trabulsi EJ, Feng FY, Filvaroff EH, Hege K, Rathkopf D, Knudsen KE. Dylgjeri E, et al. Among authors: schiewer mj. Clin Cancer Res. 2019 Sep 15;25(18):5623-5637. doi: 10.1158/1078-0432.CCR-18-2207. Epub 2019 Jul 2. Clin Cancer Res. 2019. PMID: 31266833 Free PMC article.
USP22 Functions as an Oncogenic Driver in Prostate Cancer by Regulating Cell Proliferation and DNA Repair.
McCann JJ, Vasilevskaya IA, Poudel Neupane N, Shafi AA, McNair C, Dylgjeri E, Mandigo AC, Schiewer MJ, Schrecengost RS, Gallagher P, Stanek TJ, McMahon SB, Berman-Booty LD, Ostrander WF Jr, Knudsen KE. McCann JJ, et al. Among authors: schiewer mj. Cancer Res. 2020 Feb 1;80(3):430-443. doi: 10.1158/0008-5472.CAN-19-1033. Epub 2019 Nov 18. Cancer Res. 2020. PMID: 31740444 Free PMC article.
Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer.
Mandigo AC, Shafi AA, McCann JJ, Yuan W, Laufer TS, Bogdan D, Gallagher L, Dylgjeri E, Semenova G, Vasilevskaya IA, Schiewer MJ, McNair CM, de Bono JS, Knudsen KE. Mandigo AC, et al. Among authors: schiewer mj. Cancer Res. 2022 Jan 15;82(2):221-234. doi: 10.1158/0008-5472.CAN-21-1159. Epub 2021 Oct 8. Cancer Res. 2022. PMID: 34625422 Free PMC article.
A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer.
Dylgjeri E, Kothari V, Shafi AA, Semenova G, Gallagher PT, Guan YF, Pang A, Goodwin JF, Irani S, McCann JJ, Mandigo AC, Chand S, McNair CM, Vasilevskaya I, Schiewer MJ, Lallas CD, McCue PA, Gomella LG, Seifert EL, Carroll JS, Butler LM, Holst J, Kelly WK, Knudsen KE. Dylgjeri E, et al. Among authors: schiewer mj. Clin Cancer Res. 2022 Apr 1;28(7):1446-1459. doi: 10.1158/1078-0432.CCR-21-1846. Clin Cancer Res. 2022. PMID: 35078861 Free PMC article.
48 results