Zhang H - Search Results

1

Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.

Bian YC, Meng J, Hu T, Ma S, Huang CR, Zhang FY, Wu QH, Zhang H, Chen XY, Miao LY. Bian YC, et al. Among authors: zhang fy, zhang h. Diabetes Obes Metab. 2024 Jul;26(7):2860-2868. doi: 10.1111/dom.15605. Epub 2024 Apr 22. Diabetes Obes Metab. 2024. PMID: 38646838

2

Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein.

Meng J, Liu XY, Ma S, Zhang H, Yu SD, Zhang YF, Chen MX, Zhu XY, Liu Y, Yi L, Ding XL, Chen XY, Miao LY, Zhong DF. Meng J, et al. Among authors: zhang yf, zhang h. Acta Pharmacol Sin. 2019 Jul;40(7):980-988. doi: 10.1038/s41401-018-0176-6. Epub 2018 Oct 31. Acta Pharmacol Sin. 2019. PMID: 30382184 Free PMC article.

3

Mass balance, pharmacokinetics and pharmacodynamics of intravenous HSK3486, a novel anaesthetic, administered to healthy subjects.

Bian Y, Zhang H, Ma S, Jiao Y, Yan P, Liu X, Ma S, Xiong Y, Gu Z, Yu Z, Huang C, Miao L. Bian Y, et al. Among authors: zhang h. Br J Clin Pharmacol. 2021 Jan;87(1):93-105. doi: 10.1111/bcp.14363. Epub 2020 Aug 3. Br J Clin Pharmacol. 2021. PMID: 32415708 Free article. Clinical Trial.

4

Pharmacokinetics, mass balance, and metabolism of [¹⁴C]vicagrel, a novel irreversible P2Y₁₂ inhibitor in humans.

Zheng YD, Zhang H, Zhan Y, Bian YC, Ma S, Gan HX, Lai XJ, Liu YQ, Gong YC, Liu XF, Sun HB, Li YG, Zhong DF, Miao LY, Diao XX. Zheng YD, et al. Among authors: zhang h. Acta Pharmacol Sin. 2021 Sep;42(9):1535-1546. doi: 10.1038/s41401-020-00547-7. Epub 2020 Nov 26. Acta Pharmacol Sin. 2021. PMID: 33244163 Free PMC article.

5

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans.

Meng J, Zhang H, Bao JJ, Chen ZD, Liu XY, Zhang YF, Jiang Y, Miao LY, Zhong DF. Meng J, et al. Among authors: zhang yf, zhang h. Acta Pharmacol Sin. 2022 Feb;43(2):494-503. doi: 10.1038/s41401-021-00667-8. Epub 2021 Apr 29. Acta Pharmacol Sin. 2022. PMID: 33927359 Free PMC article.

6

Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [¹⁴C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase.

Zheng Y, Zhang H, Liu M, Li G, Ma S, Zhang Z, Lin H, Zhan Y, Chen Z, Zhong D, Miao L, Diao X. Zheng Y, et al. Among authors: zhang z, zhang h. Drug Metab Dispos. 2022 Jun;50(6):798-808. doi: 10.1124/dmd.121.000581. Epub 2021 Dec 3. Drug Metab Dispos. 2022. PMID: 34862252

7

Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP-ribose) polymerase inhibitor, in subjects with advanced solid cancers.

Bian Y, Meng J, Ma S, Li G, Wang Y, Li S, Liu L, Huang C, Zhang H, Zhong D, Miao L. Bian Y, et al. Among authors: zhang h. Br J Clin Pharmacol. 2022 Jul;88(7):3307-3320. doi: 10.1111/bcp.15256. Epub 2022 Feb 28. Br J Clin Pharmacol. 2022. PMID: 35112382 Free article. Clinical Trial.

8

Absorption, metabolism, and excretion of [¹⁴C]YY-20394, a highly selective PI3K-Delta inhibitor in humans.

Yu J, Zhang H, Zhang Y, Zhan Y, Ma S, Hu T, Zhang N, Lou Y, Bao H, Xu Z, Zhong D, Miao L, Diao X. Yu J, et al. Among authors: zhang n, zhang h, zhang y. Xenobiotica. 2022 Mar;52(3):254-264. doi: 10.1080/00498254.2022.2062581. Epub 2022 Apr 11. Xenobiotica. 2022. PMID: 35373704

9

Mass balance study of [¹⁴C]SHR0302, a selective and potent JAK1 inhibitor in humans.

Ge X, Ma S, Yan S, Wu Y, Chen C, Tang C, Zhan Y, Bian YC, Shen K, Feng S, Gao X, Zhong D, Zhang H, Miao LY, Diao XX. Ge X, et al. Among authors: zhang h. Xenobiotica. 2023 Feb;53(2):69-83. doi: 10.1080/00498254.2023.2176267. Epub 2023 Feb 12. Xenobiotica. 2023. PMID: 36745485

10

A mass balance study of [¹⁴C]SHR6390 (dalpiciclib), a selective and potent CDK4/6 inhibitor in humans.

Zhang H, Yan S, Zhan Y, Ma S, Bian Y, Li S, Tian J, Li G, Zhong D, Diao X, Miao L. Zhang H, et al. Front Pharmacol. 2023 Mar 31;14:1116073. doi: 10.3389/fphar.2023.1116073. eCollection 2023. Front Pharmacol. 2023. PMID: 37063263 Free PMC article.

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