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Protein Allostery Study in Cells Using NMR Spectroscopy.
Chen X, Zhang X, Qin M, Chen J, Wang M, Liu Z, An L, Song X, Yao L. Chen X, et al. Among authors: an l. Anal Chem. 2024 May 7;96(18):7065-7072. doi: 10.1021/acs.analchem.4c00360. Epub 2024 Apr 23. Anal Chem. 2024. PMID: 38652079
Polyol and sugar osmolytes can shorten protein hydrogen bonds to modulate function.
Li J, Chen J, An L, Yuan X, Yao L. Li J, et al. Among authors: an l. Commun Biol. 2020 Sep 23;3(1):528. doi: 10.1038/s42003-020-01260-1. Commun Biol. 2020. PMID: 32968183 Free PMC article.
Polyol and sugar osmolytes are commonly used in therapeutic protein formulations. How they may affect protein structure and function is an important question. In this work, through NMR measurements, we show that glycerol and sorbitol (polyols), as well as glucose (sugar), …
Polyol and sugar osmolytes are commonly used in therapeutic protein formulations. How they may affect protein structure and function is a …
Entropy Drives the Formation of Salt Bridges in the Protein GB3.
Zhang N, Wang Y, An L, Song X, Huang Q, Liu Z, Yao L. Zhang N, et al. Among authors: an l. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7601-7604. doi: 10.1002/anie.201702968. Epub 2017 May 19. Angew Chem Int Ed Engl. 2017. PMID: 28474463
3,113 results