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Apramycin efficacy against carbapenem- and aminoglycoside-resistant Escherichia coli and Klebsiella pneumoniae in murine blood stream infection models.
Frimodt-Møller N, Hansen JU, Plattner M, Huseby DL, Almind SR, Haldimann K, Gysin M, Petersson A, Ercan O, Ganz L, Hughes D, Lundberg CV, Hobbie SN. Frimodt-Møller N, et al. Among authors: huseby dl. Int J Antimicrob Agents. 2024 Apr 21:107181. doi: 10.1016/j.ijantimicag.2024.107181. Online ahead of print. Int J Antimicrob Agents. 2024. PMID: 38653351 Free article.
In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii.
Juhas M, Widlake E, Teo J, Huseby DL, Tyrrell JM, Polikanov YS, Ercan O, Petersson A, Cao S, Aboklaish AF, Rominski A, Crich D, Böttger EC, Walsh TR, Hughes D, Hobbie SN. Juhas M, et al. Among authors: huseby dl. J Antimicrob Chemother. 2019 Apr 1;74(4):944-952. doi: 10.1093/jac/dky546. J Antimicrob Chemother. 2019. PMID: 30629184 Free PMC article.
Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.
Becker K, Cao S, Nilsson A, Erlandsson M, Hotop SK, Kuka J, Hansen J, Haldimann K, Grinberga S, Berruga-Fernández T, Huseby DL, Shariatgorji R, Lindmark E, Platzack B, Böttger EC, Crich D, Friberg LE, Vingsbo Lundberg C, Hughes D, Brönstrup M, Andrén PE, Liepinsh E, Hobbie SN. Becker K, et al. Among authors: huseby dl. EBioMedicine. 2021 Nov;73:103652. doi: 10.1016/j.ebiom.2021.103652. Epub 2021 Nov 2. EBioMedicine. 2021. PMID: 34740109 Free PMC article.
32 results