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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease.
Huang B, Zeng Z, Kim S, Fausto CC, Koppitch K, Li H, Li Z, Chen X, Guo J, Zhang CC, Ma T, Medina P, Schreiber ME, Xia MW, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, Lindström NO, McMahon AP, Li Z. Huang B, et al. Among authors: gnedeva k. Cell Stem Cell. 2024 Apr 22:S1934-5909(24)00129-2. doi: 10.1016/j.stem.2024.04.002. Online ahead of print. Cell Stem Cell. 2024. PMID: 38692273
Large-scale annotated dataset for cochlear hair cell detection and classification.
Buswinka CJ, Rosenberg DB, Simikyan RG, Osgood RT, Fernandez K, Nitta H, Hayashi Y, Liberman LW, Nguyen E, Yildiz E, Kim J, Jarysta A, Renauld J, Wesson E, Wang H, Thapa P, Bordiga P, McMurtry N, Llamas J, Kitcher SR, López-Porras AI, Cui R, Behnammanesh G, Bird JE, Ballesteros A, Vélez-Ortega AC, Edge ASB, Deans MR, Gnedeva K, Shrestha BR, Manor U, Zhao B, Ricci AJ, Tarchini B, Basch ML, Stepanyan R, Landegger LD, Rutherford MA, Liberman MC, Walters BJ, Kros CJ, Richardson GP, Cunningham LL, Indzhykulian AA. Buswinka CJ, et al. Among authors: gnedeva k. Sci Data. 2024 Apr 23;11(1):416. doi: 10.1038/s41597-024-03218-y. Sci Data. 2024. PMID: 38653806 Free PMC article.
Large-scale annotated dataset for cochlear hair cell detection and classification.
Buswinka CJ, Rosenberg DB, Simikyan RG, Osgood RT, Fernandez K, Nitta H, Hayashi Y, Liberman LW, Nguyen E, Yildiz E, Kim J, Jarysta A, Renauld J, Wesson E, Thapa P, Bordiga P, McMurtry N, Llamas J, Kitcher SR, López-Porras AI, Cui R, Behnammanesh G, Bird JE, Ballesteros A, Vélez-Ortega AC, Edge AS, Deans MR, Gnedeva K, Shrestha BR, Manor U, Zhao B, Ricci AJ, Tarchini B, Basch M, Stepanyan RS, Landegger LD, Rutherford M, Liberman MC, Walters BJ, Kros CJ, Richardson GP, Cunningham LL, Indzhykulian AA. Buswinka CJ, et al. Among authors: gnedeva k. bioRxiv [Preprint]. 2023 Sep 1:2023.08.30.553559. doi: 10.1101/2023.08.30.553559. bioRxiv. 2023. PMID: 37693382 Free PMC article. Updated. Preprint.
Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids.
Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Lindström NO, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, McMahon AP, Li Z. Huang B, et al. Among authors: gnedeva k. bioRxiv [Preprint]. 2023 May 25:2023.05.25.542343. doi: 10.1101/2023.05.25.542343. bioRxiv. 2023. PMID: 37293038 Free PMC article. Preprint.
Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs.
Kastan NR, Oak S, Liang R, Baxt L, Myers RW, Ginn J, Liverton N, Huggins DJ, Pichardo J, Paul M, Carroll TS, Nagiel A, Gnedeva K, Hudspeth AJ. Kastan NR, et al. Among authors: gnedeva k. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2206113119. doi: 10.1073/pnas.2206113119. Epub 2022 Jul 8. Proc Natl Acad Sci U S A. 2022. PMID: 35867764 Free PMC article.
Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal.
Gnedeva K, Wang X, McGovern MM, Barton M, Tao L, Trecek T, Monroe TO, Llamas J, Makmura W, Martin JF, Groves AK, Warchol M, Segil N. Gnedeva K, et al. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13552-13561. doi: 10.1073/pnas.2000175117. Epub 2020 Jun 1. Proc Natl Acad Sci U S A. 2020. PMID: 32482884 Free PMC article.
18 results