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CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing.
Nat Commun. 2024 Apr 24;15(1):3478. doi: 10.1038/s41467-024-47800-9.
Nat Commun. 2024.
PMID: 38658578
Free PMC article.
Eukaryotic-driven directed evolution of Cas9 nucleases.
Ruta GV, Ciciani M, Kheir E, Gentile MD, Amistadi S, Casini A, Cereseto A.
Ruta GV, et al. Among authors: amistadi s.
Genome Biol. 2024 Mar 25;25(1):79. doi: 10.1186/s13059-024-03215-9.
Genome Biol. 2024.
PMID: 38528620
Free PMC article.
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An optimized SpCas9 high-fidelity variant for direct protein delivery.
Pedrazzoli E, Bianchi A, Umbach A, Amistadi S, Brusson M, Frati G, Ciciani M, Badowska KA, Arosio D, Miccio A, Cereseto A, Casini A.
Pedrazzoli E, et al. Among authors: amistadi s.
Mol Ther. 2023 Jul 5;31(7):2257-2265. doi: 10.1016/j.ymthe.2023.03.007. Epub 2023 Mar 10.
Mol Ther. 2023.
PMID: 36905119
Free article.
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Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor.
Amistadi S, Maule G, Ciciani M, Ensinck MM, De Keersmaecker L, Ramalho AS, Guidone D, Buccirossi M, Galietta LJV, Carlon MS, Cereseto A.
Amistadi S, et al.
Mol Ther. 2023 Jun 7;31(6):1647-1660. doi: 10.1016/j.ymthe.2023.03.004. Epub 2023 Mar 9.
Mol Ther. 2023.
PMID: 36895161
Free article.
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