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JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Fortelny N, Farlik M, Fife V, Gorki AD, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Ravi Sundar Jose Geetha A, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T, Müller M, Bock C. Fortelny N, et al. Among authors: krausgruber t. Nat Immunol. 2024 May;25(5):847-859. doi: 10.1038/s41590-024-01804-1. Epub 2024 Apr 24. Nat Immunol. 2024. PMID: 38658806 Free PMC article.
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.
Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman MW, Eder T, Abdallah DI, Maurer B, Wagner C, Schönefeldt S, Spirk K, Pichler A, Pemovska T, Schweicker C, Pölöske D, Hubanic E, Jungherz D, Müller TA, Aung MMK, Orlova A, Pham HTT, Zimmel K, Krausgruber T, Bock C, Müller M, Dahlhoff M, Boersma A, Rülicke T, Fleck R, de Araujo ED, Gunning PT, Aittokallio T, Mustjoki S, Sanda T, Hartmann S, Grebien F, Hoermann G, Haferlach T, Staber PB, Neubauer HA, Look AT, Herling M, Moriggl R. Suske T, et al. Among authors: krausgruber t. J Clin Invest. 2024 Apr 15;134(8):e168536. doi: 10.1172/JCI168536. J Clin Invest. 2024. PMID: 38618957 Free PMC article.
Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice.
Hevesi Z, Bakker J, Tretiakov EO, Adori C, Raabgrund A, Barde SS, Caramia M, Krausgruber T, Ladstätter S, Bock C, Hökfelt T, Harkany T. Hevesi Z, et al. Among authors: krausgruber t. Nat Commun. 2024 Mar 29;15(1):2762. doi: 10.1038/s41467-024-47054-5. Nat Commun. 2024. PMID: 38553447 Free PMC article.
Aberrant Lipid Metabolism in Macrophages Is Associated with Granuloma Formation in Sarcoidosis.
Lim CX, Redl A, Kleissl L, Pandey RV, Mayerhofer C, El Jammal T, Mazic M, Gonzales K, Sukhbaatar N, Krausgruber T, Bock C, Hengstschläger M, Calender A, Pacheco Y, Stary G, Weichhart T. Lim CX, et al. Among authors: krausgruber t. Am J Respir Crit Care Med. 2024 May 1;209(9):1152-1164. doi: 10.1164/rccm.202307-1273OC. Am J Respir Crit Care Med. 2024. PMID: 38353578
Efficacy and safety of mTOR inhibition in cutaneous sarcoidosis: a single-centre trial.
Redl A, Doberer K, Unterluggauer L, Kleissl L, Krall C, Mayerhofer C, Reininger B, Stary V, Zila N, Weninger W, Weichhart T, Bock C, Krausgruber T, Stary G. Redl A, et al. Among authors: krausgruber t. Lancet Rheumatol. 2024 Feb;6(2):e81-e91. doi: 10.1016/S2665-9913(23)00302-8. Lancet Rheumatol. 2024. PMID: 38267106 Clinical Trial.
Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.
Moorlag SJCFM, Folkman L, Ter Horst R, Krausgruber T, Barreca D, Schuster LC, Fife V, Matzaraki V, Li W, Reichl S, Mourits VP, Koeken VACM, de Bree LCJ, Dijkstra H, Lemmers H, van Cranenbroek B, van Rijssen E, Koenen HJPM, Joosten I, Xu CJ, Li Y, Joosten LAB, van Crevel R, Netea MG, Bock C. Moorlag SJCFM, et al. Among authors: krausgruber t. Immunity. 2024 Jan 9;57(1):171-187.e14. doi: 10.1016/j.immuni.2023.12.005. Immunity. 2024. PMID: 38198850 Free article.
Multipotent progenitors instruct ontogeny of the superior colliculus.
Cheung G, Pauler FM, Koppensteiner P, Krausgruber T, Streicher C, Schrammel M, Gutmann-Özgen N, Ivec AE, Bock C, Shigemoto R, Hippenmeyer S. Cheung G, et al. Among authors: krausgruber t. Neuron. 2024 Jan 17;112(2):230-246.e11. doi: 10.1016/j.neuron.2023.11.009. Epub 2023 Dec 13. Neuron. 2024. PMID: 38096816 Free article.
Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation.
Krausgruber T, Redl A, Barreca D, Doberer K, Romanovskaia D, Dobnikar L, Guarini M, Unterluggauer L, Kleissl L, Atzmüller D, Mayerhofer C, Kopf A, Saluzzo S, Lim CX, Rexie P, Weichhart T, Bock C, Stary G. Krausgruber T, et al. Immunity. 2023 Feb 14;56(2):289-306.e7. doi: 10.1016/j.immuni.2023.01.014. Epub 2023 Feb 6. Immunity. 2023. PMID: 36750099 Free PMC article.
Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation.
Pandey RV, Strobl J, Redl A, Unterluggauer L, Gail L, Kleissl L, Müller S, Atzmüller D, Fife-Gernedl V, Krausgruber T, Knaus H, Mitterbauer M, Wohlfarth P, Rabitsch W, Bock C, Stary G. Pandey RV, et al. Among authors: krausgruber t. Clin Immunol. 2023 Mar;248:109245. doi: 10.1016/j.clim.2023.109245. Epub 2023 Jan 23. Clin Immunol. 2023. PMID: 36702179 Free article.
48 results