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Tumorigenesis driven by the BRAFV600E oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion.
bioRxiv [Preprint]. 2024 Apr 20:2023.11.21.568071. doi: 10.1101/2023.11.21.568071.
bioRxiv. 2024.
PMID: 38659913
Free PMC article.
Preprint.
Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis.
Mukherjee R, Vanaja KG, Boyer JA, Gadal S, Solomon H, Chandarlapaty S, Levchenko A, Rosen N.
Mukherjee R, et al. Among authors: gadal s.
Mol Cell. 2021 Feb 18;81(4):708-723.e5. doi: 10.1016/j.molcel.2021.01.033.
Mol Cell. 2021.
PMID: 33606974
Free PMC article.
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A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation.
Yaeger R, McKean MA, Haq R, Beck JT, Taylor MH, Cohen JE, Bowles DW, Gadgeel SM, Mihalcioiu C, Papadopoulos KP, Diamond EL, Sturtz KB, Feng G, Drescher SK, Reddy MB, Sengupta B, Maity AK, Brown SA, Singh A, Brown EN, Baer BR, Wong J, Mou TC, Wu WI, Kahn DR, Gadal S, Rosen N, Gaudino JJ, Lee PA, Hartley DP, Rothenberg SM.
Yaeger R, et al. Among authors: gadal s.
Cancer Discov. 2024 Apr 30. doi: 10.1158/2159-8290.CD-24-0024. Online ahead of print.
Cancer Discov. 2024.
PMID: 38691346
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eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
Boyer JA, Sharma M, Dorso MA, Mai N, Amor C, Reiter JM, Kannan R, Gadal S, Xu J, Miele M, Li Z, Chen X, Chang Q, Pareja F, Worland S, Warner D, Sperry S, Chiang GG, Thompson PA, Yang G, Ouerfelli O, de Stanchina E, Wendel HG, Rosen EY, Chandarlapaty S, Rosen N.
Boyer JA, et al. Among authors: gadal s.
bioRxiv [Preprint]. 2024 May 11:2024.05.08.593195. doi: 10.1101/2024.05.08.593195.
bioRxiv. 2024.
PMID: 38766126
Free PMC article.
Preprint.
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Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors.
Lito P, Saborowski A, Yue J, Solomon M, Joseph E, Gadal S, Saborowski M, Kastenhuber E, Fellmann C, Ohara K, Morikami K, Miura T, Lukacs C, Ishii N, Lowe S, Rosen N.
Lito P, et al. Among authors: gadal s.
Cancer Cell. 2014 May 12;25(5):697-710. doi: 10.1016/j.ccr.2014.03.011. Epub 2014 Apr 17.
Cancer Cell. 2014.
PMID: 24746704
Free PMC article.
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Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2.
Mao N, Gao D, Hu W, Gadal S, Hieronymus H, Wang S, Lee YS, Sullivan P, Zhang Z, Choi D, Rosen N, Sawyers CL, Gopalan A, Chen Y, Carver BS.
Mao N, et al. Among authors: gadal s.
Cancer Res. 2020 Apr 1;80(7):1428-1437. doi: 10.1158/0008-5472.CAN-19-1394. Epub 2020 Feb 3.
Cancer Res. 2020.
PMID: 32015092
Free PMC article.
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Multi-source datasets acquired over Toulouse (France) in 2021 for urban microclimate studies during the CAMCATT/AI4GEO field campaign.
Roupioz L, Briottet X, Adeline K, Al Bitar A, Barbon-Dubosc D, Barda-Chatain R, Barillot P, Bridier S, Carroll E, Cassante C, Cerbelaud A, Déliot P, Doublet P, Dupouy PE, Gadal S, Guernouti S, De Guilhem De Lataillade A, Lemonsu A, Llorens R, Luhahe R, Michel A, Moussous A, Musy M, Nerry F, Poutier L, Rodler A, Riviere N, Riviere T, Roujean JL, Roy A, Schilling A, Skokovic D, Sobrino J.
Roupioz L, et al. Among authors: gadal s.
Data Brief. 2023 Apr 3;48:109109. doi: 10.1016/j.dib.2023.109109. eCollection 2023 Jun.
Data Brief. 2023.
PMID: 37122929
Free PMC article.
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Antioxidants in central nervous system diseases: preclinical promise and translational challenges.
Kamat CD, Gadal S, Mhatre M, Williamson KS, Pye QN, Hensley K.
Kamat CD, et al. Among authors: gadal s.
J Alzheimers Dis. 2008 Nov;15(3):473-93. doi: 10.3233/jad-2008-15314.
J Alzheimers Dis. 2008.
PMID: 18997301
Free PMC article.
Review.
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