Palomo V - Search Results

1

Designing multitarget ligands for neurodegenerative diseases with improved permeability trough PLGA nanoencapsulation.

Nozal V, Fernández-Gómez P, García-Rubia A, Martínez-González L, Cuevas EP, Carro E, Palomo V, Martínez A. Nozal V, et al. Among authors: palomo v. Biomed Pharmacother. 2024 Apr 24;175:116626. doi: 10.1016/j.biopha.2024.116626. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38663103 Free article.

2

From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein-Templated Synthesis.

Nozal V, García-Rubia A, Cuevas EP, Pérez C, Tosat-Bitrián C, Bartolomé F, Carro E, Ramírez D, Palomo V, Martínez A. Nozal V, et al. Among authors: palomo v. Angew Chem Int Ed Engl. 2021 Aug 23;60(35):19344-19354. doi: 10.1002/anie.202106295. Epub 2021 Jul 26. Angew Chem Int Ed Engl. 2021. PMID: 34169618 Free PMC article.

3

TDP-43 Pathology and Prionic Behavior in Human Cellular Models of Alzheimer's Disease Patients.

Cuevas EP, Rodríguez-Fernández A, Palomo V, Martínez A, Martín-Requero Á. Cuevas EP, et al. Among authors: palomo v. Biomedicines. 2022 Feb 5;10(2):385. doi: 10.3390/biomedicines10020385. Biomedicines. 2022. PMID: 35203594 Free PMC article.

4

Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2014-2015).

Palomo V, Martinez A. Palomo V, et al. Expert Opin Ther Pat. 2017 Jun;27(6):657-666. doi: 10.1080/13543776.2017.1259412. Epub 2016 Nov 21. Expert Opin Ther Pat. 2017. PMID: 27828716 Free article. Review.

5

TDP-43: A Key Therapeutic Target beyond Amyotrophic Lateral Sclerosis.

Palomo V, Tosat-Bitrian C, Nozal V, Nagaraj S, Martin-Requero A, Martinez A. Palomo V, et al. ACS Chem Neurosci. 2019 Mar 20;10(3):1183-1196. doi: 10.1021/acschemneuro.9b00026. Epub 2019 Mar 4. ACS Chem Neurosci. 2019. PMID: 30785719 Free article. Review.

6

Protein kinase inhibitors for amyotrophic lateral sclerosis therapy.

Palomo V, Nozal V, Rojas-Prats E, Gil C, Martinez A. Palomo V, et al. Br J Pharmacol. 2021 Mar;178(6):1316-1335. doi: 10.1111/bph.15221. Epub 2020 Aug 31. Br J Pharmacol. 2021. PMID: 32737989 Free article. Review.

7

TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.

Nozal V, Martínez-González L, Gomez-Almeria M, Gonzalo-Consuegra C, Santana P, Chaikuad A, Pérez-Cuevas E, Knapp S, Lietha D, Ramírez D, Petralla S, Monti B, Gil C, Martín-Requero A, Palomo V, de Lago E, Martinez A. Nozal V, et al. Among authors: palomo v. J Med Chem. 2022 Jan 27;65(2):1585-1607. doi: 10.1021/acs.jmedchem.1c01942. Epub 2022 Jan 3. J Med Chem. 2022. PMID: 34978799

8

TTBK1 and CK1 inhibitors restore TDP-43 pathology and avoid disease propagation in lymphoblast from Alzheimer's disease patients.

Martinez-Gonzalez L, Cuevas EP, Tosat-Bitrián C, Nozal V, Gil C, Palomo V, Martín-Requero Á, Martinez A. Martinez-Gonzalez L, et al. Among authors: palomo v. Front Mol Neurosci. 2023 Aug 9;16:1243277. doi: 10.3389/fnmol.2023.1243277. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37621404 Free PMC article.

9

Casein kinase 1 inhibitor avoids TDP-43 pathology propagation in a patient-derived cellular model of amyotrophic lateral sclerosis.

Cuevas EP, Martinez-Gonzalez L, Gordillo C, Tosat-Bitrián C, Pérez de la Lastra C, Sáenz A, Gil C, Palomo V, Martin-Requero Á, Martinez A. Cuevas EP, et al. Among authors: palomo v. Neurobiol Dis. 2024 Mar;192:106430. doi: 10.1016/j.nbd.2024.106430. Epub 2024 Feb 5. Neurobiol Dis. 2024. PMID: 38325718 Free article.

10

Efficacy of a benzothiazole-based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis.

Benítez-Fernández R, Josa-Prado F, Sánchez E, Lao Y, García-Rubia A, Cumella J, Martínez A, Palomo V, de Castro F. Benítez-Fernández R, et al. Among authors: palomo v. CNS Neurosci Ther. 2024 Jan;30(1):e14552. doi: 10.1111/cns.14552. CNS Neurosci Ther. 2024. PMID: 38287523 Free PMC article.

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