Burchett W - Search Results

1

Species-Specific Unbound Fraction Differences in Highly Bound PFAS: A Comparative Study across Human, Rat, and Mouse Plasma and Albumin.

Ryu S, Burchett W, Zhang S, Modaresi SMS, Agudelo Areiza J, Kaye E, Fischer FC, Slitt AL. Ryu S, et al. Among authors: burchett w. Toxics. 2024 Mar 29;12(4):253. doi: 10.3390/toxics12040253. Toxics. 2024. PMID: 38668476 Free PMC article.

2

Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes.

Liu J, Vernikovskaya D, Bora G, Carlo A, Burchett W, Jordan S, Tang LWT, Yang J, Che Y, Chang G, Troutman MD, Di L. Liu J, et al. Among authors: burchett w. AAPS J. 2024 Mar 28;26(3):36. doi: 10.1208/s12248-024-00908-8. AAPS J. 2024. PMID: 38546903

3

Comparison of Tumor Binding Across Tumor Types and Cell Lines to Support Free Drug Considerations for Oncology Drug Discovery.

Jordan S, Ryu S, Burchett W, Davis C, Jones R, Zhang S, Zueva L, Chang G, Di L. Jordan S, et al. Among authors: burchett w. J Pharm Sci. 2024 Mar;113(3):826-835. doi: 10.1016/j.xphs.2023.11.024. Epub 2023 Nov 30. J Pharm Sci. 2024. PMID: 38042346

4

Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.

Doran AC, Burchett W, Landers C, Gualtieri GM, Balesano A, Eng H, Dantonio AL, Goosen TC, Obach RS. Doran AC, et al. Among authors: burchett w. Drug Metab Dispos. 2022 Jul 1:DMD-AR-2022-000884. doi: 10.1124/dmd.122.000884. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35777846 Free article.

5

An improved method for cytochrome p450 reaction phenotyping using a sequential qualitative-then-quantitative approach.

Doran AC, Dantonio AL, Gualtieri GM, Balesano A, Landers C, Burchett W, Goosen TC, Obach RS. Doran AC, et al. Among authors: burchett w. Drug Metab Dispos. 2022 Jul 1:DMD-AR-2022-000883. doi: 10.1124/dmd.122.000883. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35777845 Free article.

6

Effects of low temperature on blood-to-plasma ratio measurement.

Novak JJ, Burchett W, Di L. Novak JJ, et al. Among authors: burchett w. Biopharm Drug Dispos. 2021 May;42(5):234-241. doi: 10.1002/bdd.2265. Epub 2021 Mar 15. Biopharm Drug Dispos. 2021. PMID: 33625733

7

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries.

Foley TL, Burchett W, Chen Q, Flanagan ME, Kapinos B, Li X, Montgomery JI, Ratnayake AS, Zhu H, Peakman MC. Foley TL, et al. Among authors: burchett w. SLAS Discov. 2021 Feb;26(2):263-280. doi: 10.1177/2472555220979589. Epub 2021 Jan 8. SLAS Discov. 2021. PMID: 33412987 Free article.

8

Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR Methods.

Mathew S, Tess D, Burchett W, Chang G, Woody N, Keefer C, Orozco C, Lin J, Jordan S, Yamazaki S, Jones R, Di L. Mathew S, et al. Among authors: burchett w. J Pharm Sci. 2021 Apr;110(4):1799-1823. doi: 10.1016/j.xphs.2020.12.005. Epub 2020 Dec 16. J Pharm Sci. 2021. PMID: 33338491

9

Optimal designs for pairwise calculation: An application to free energy perturbation in minimizing prediction variability.

Yang Q, Burchett W, Steeno GS, Liu S, Yang M, Mobley DL, Hou X. Yang Q, et al. Among authors: burchett w. J Comput Chem. 2020 Jan 30;41(3):247-257. doi: 10.1002/jcc.26095. Epub 2019 Nov 13. J Comput Chem. 2020. PMID: 31721260 Free PMC article.

10

Evaluation of Fraction Unbound Across 7 Tissues of 5 Species.

Ryu S, Tess D, Chang G, Keefer C, Burchett W, Steeno GS, Novak JJ, Patel R, Atkinson K, Riccardi K, Di L. Ryu S, et al. Among authors: burchett w. J Pharm Sci. 2020 Feb;109(2):1178-1190. doi: 10.1016/j.xphs.2019.10.060. Epub 2019 Nov 5. J Pharm Sci. 2020. PMID: 31704191

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