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AAV-Mediated CAG-Targeting Selectively Reduces Polyglutamine-Expanded Protein and Attenuates Disease Phenotypes in a Spinocerebellar Ataxia Mouse Model.
Niewiadomska-Cimicka A, Fievet L, Surdyka M, Jesion E, Keime C, Singer E, Eisenmann A, Kalinowska-Poska Z, Nguyen HHP, Fiszer A, Figiel M, Trottier Y. Niewiadomska-Cimicka A, et al. Among authors: figiel m. Int J Mol Sci. 2024 Apr 15;25(8):4354. doi: 10.3390/ijms25084354. Int J Mol Sci. 2024. PMID: 38673939 Free PMC article.
Mouse ataxin-3 functional knock-out model.
Switonski PM, Fiszer A, Kazmierska K, Kurpisz M, Krzyzosiak WJ, Figiel M. Switonski PM, et al. Among authors: figiel m. Neuromolecular Med. 2011 Mar;13(1):54-65. doi: 10.1007/s12017-010-8137-3. Epub 2010 Oct 14. Neuromolecular Med. 2011. PMID: 20945165 Free PMC article.
Altered Levels of Proteins and Phosphoproteins, in the Absence of Early Causative Transcriptional Changes, Shape the Molecular Pathogenesis in the Brain of Young Presymptomatic Ki91 SCA3/MJD Mouse.
Wiatr K, Piasecki P, Marczak Ł, Wojciechowski P, Kurkowiak M, Płoski R, Rydzanicz M, Handschuh L, Jungverdorben J, Brüstle O, Figlerowicz M, Figiel M. Wiatr K, et al. Among authors: figiel m. Mol Neurobiol. 2019 Dec;56(12):8168-8202. doi: 10.1007/s12035-019-01643-4. Epub 2019 Jun 14. Mol Neurobiol. 2019. PMID: 31201651 Free PMC article.
53 results