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Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Klevstig M, Arif M, Mannila M, Svedlund S, Mardani I, Ståhlman M, Andersson L, Lindbom M, Miljanovic A, Franco-Cereceda A, Eriksson P, Jeppsson A, Gan LM, Levin M, Mardinoglu A, Ehrenborg E, Borén J. Klevstig M, et al. Among authors: levin m. J Mol Cell Cardiol. 2019 Dec;137:1-8. doi: 10.1016/j.yjmcc.2019.09.003. Epub 2019 Sep 15. J Mol Cell Cardiol. 2019. PMID: 31533023 Free article.
Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart.
Mardani I, Tomas Dalen K, Drevinge C, Miljanovic A, Ståhlman M, Klevstig M, Scharin Täng M, Fogelstrand P, Levin M, Ekstrand M, Nair S, Redfors B, Omerovic E, Andersson L, Kimmel AR, Borén J, Levin MC. Mardani I, et al. Among authors: levin m, levin mc. Sci Rep. 2019 May 6;9(1):6909. doi: 10.1038/s41598-019-43335-y. Sci Rep. 2019. PMID: 31061399 Free PMC article.
Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice.
Johansson ME, Zhang XY, Edfeldt K, Lundberg AM, Levin MC, Borén J, Li W, Yuan XM, Folkersen L, Eriksson P, Hedin U, Low H, Sviridov D, Rios FJ, Hansson GK, Yan ZQ. Johansson ME, et al. Among authors: levin mc. Eur J Immunol. 2014 Oct;44(10):3081-92. doi: 10.1002/eji.201444755. Epub 2014 Aug 25. Eur J Immunol. 2014. PMID: 25042478 Free article.
Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation.
Levin MC, Jirholt P, Wramstedt A, Johansson ME, Lundberg AM, Trajkovska MG, Ståhlman M, Fogelstrand P, Brisslert M, Fogelstrand L, Yan ZQ, Hansson GK, Björkbacka H, Olofsson SO, Borén J. Levin MC, et al. Circ Res. 2011 Nov 11;109(11):1210-8. doi: 10.1161/CIRCRESAHA.111.246702. Epub 2011 Sep 29. Circ Res. 2011. PMID: 21959219
Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor trafficking.
Andersson L, Cinato M, Mardani I, Miljanovic A, Arif M, Koh A, Lindbom M, Laudette M, Bollano E, Omerovic E, Klevstig M, Henricsson M, Fogelstrand P, Swärd K, Ekstrand M, Levin M, Wikström J, Doran S, Hyötyläinen T, Sinisalu L, Orešič M, Tivesten Å, Adiels M, Bergo MO, Proia R, Mardinoglu A, Jeppsson A, Borén J, Levin MC. Andersson L, et al. Among authors: levin m, levin mc. Eur Heart J. 2021 Nov 14;42(43):4481-4492. doi: 10.1093/eurheartj/ehab412. Eur Heart J. 2021. PMID: 34297830 Free PMC article.
Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility.
Cinato M, Mardani I, Miljanovic A, Drevinge C, Laudette M, Bollano E, Henricsson M, Tolö J, Bauza Thorbrügge M, Levin M, Lindbom M, Arif M, Pacher P, Andersson L, Olofsson CS, Borén J, Levin MC. Cinato M, et al. Among authors: levin m, levin mc. Life Sci Alliance. 2023 Jan 30;6(4):e202201690. doi: 10.26508/lsa.202201690. Print 2023 Apr. Life Sci Alliance. 2023. PMID: 36717246 Free PMC article.
Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function.
Laudette M, Lindbom M, Arif M, Cinato M, Ruiz M, Doran S, Miljanovic A, Rutberg M, Andersson L, Klevstig M, Henricsson M, Bergh PO, Bollano E, Aung N, Gustav Smith J, Pilon M, Hyötyläinen T, Orešič M, Perkins R, Mardinoglu A, Levin MC, Borén J. Laudette M, et al. Among authors: levin mc. Cardiovasc Res. 2023 Jul 4;119(7):1537-1552. doi: 10.1093/cvr/cvad041. Cardiovasc Res. 2023. PMID: 36880401 Free PMC article.
3,735 results