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Validation of a Human Challenge Model Using an LT-Expressing Enterotoxigenic E. coli Strain (LSN03-016011) and Characterization of Potential Amelioration of Disease by an Investigational Oral Vaccine Candidate (VLA1701).
Talaat KR, Porter CK, Chakraborty S, Feijoo BL, Brubaker J, Adjoodani BM, DeNearing B, Prouty MG, Poole ST, Bourgeois AL, Billingsley M, Sack DA, Eder-Lingelbach S, Taucher C. Talaat KR, et al. Among authors: porter ck. Microorganisms. 2024 Apr 3;12(4):727. doi: 10.3390/microorganisms12040727. Microorganisms. 2024. PMID: 38674674 Free PMC article.
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
Berndsen ZT, Akhtar M, Thapa M, Vickers T, Schmitz A, Torres JL, Baboo S, Kumar P, Khatoom N, Sheikh A, Hamrick M, Diedrich JK, Martinez-Bartolome S, Garrett PT, Yates JR, Turner JS, Laird RM, Poly F, Porter CK, Copps J, Ellebedy AH, Ward AB, Fleckenstein JM. Berndsen ZT, et al. Among authors: porter ck. bioRxiv [Preprint]. 2024 May 8:2024.05.08.593125. doi: 10.1101/2024.05.08.593125. bioRxiv. 2024. PMID: 38766097 Free PMC article. Preprint.
Efficacy Evaluation of an Intradermally Delivered Enterotoxigenic Escherichia coli CF Antigen I Fimbrial Tip Adhesin Vaccine Coadministered with Heat-Labile Enterotoxin with LT(R192G) against Experimental Challenge with Enterotoxigenic E. coli H10407 in Healthy Adult Volunteers.
Gutiérrez RL, Porter CK, Harro C, Talaat K, Riddle MS, DeNearing B, Brubaker J, Maciel M Jr, Laird RM, Poole S, Chakraborty S, Maier N, Sack DA, Savarino SJ. Gutiérrez RL, et al. Among authors: porter ck. Microorganisms. 2024 Jan 29;12(2):288. doi: 10.3390/microorganisms12020288. Microorganisms. 2024. PMID: 38399692 Free PMC article.
Gut microbiome and antibiotic resistance effects during travelers' diarrhea treatment and prevention.
Blake KS, Schwartz DJ, Paruthiyil S, Wang B, Ning J, Isidean SD, Burns DS, Whiteson H, Lalani T, Fraser JA, Connor P, Troth T, Porter CK, Tribble DR, Riddle MS, Gutiérrez RL, Simons MP, Dantas G. Blake KS, et al. Among authors: porter ck. mBio. 2024 Jan 16;15(1):e0279023. doi: 10.1128/mbio.02790-23. Epub 2023 Dec 12. mBio. 2024. PMID: 38085102 Free PMC article.
A First in Human Clinical Trial Assessing the Safety and Immunogenicity of Two Intradermally Delivered Enterotoxigenic Escherichia coli CFA/I Fimbrial Tip Adhesin Antigens with and without Heat-Labile Enterotoxin with Mutation LT(R192G).
Gutiérrez RL, Riddle MS, Porter CK, Maciel M Jr, Poole ST, Laird RM, Lane M, Turiansky GW, Jarell A, Savarino SJ. Gutiérrez RL, et al. Among authors: porter ck. Microorganisms. 2023 Nov 2;11(11):2689. doi: 10.3390/microorganisms11112689. Microorganisms. 2023. PMID: 38004700 Free PMC article.
Vaccine value profile for enterotoxigenic Escherichia coli (ETEC).
Khalil I, Anderson JD, Bagamian KH, Baqar S, Giersing B, Hausdorff WP, Marshall C, Porter CK, Walker RI, Bourgeois AL. Khalil I, et al. Among authors: porter ck. Vaccine. 2023 Nov 3;41 Suppl 2:S95-S113. doi: 10.1016/j.vaccine.2023.02.011. Epub 2023 Oct 6. Vaccine. 2023. PMID: 37951695 Free article.
141 results