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Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.
Elgiushy HR, Mohamed SH, Taha H, Sawaf H, Hassan Z, Abou-Taleb NA, El-Labbad EM, Hassan AS, Abouzid KAM, Hammad SF. Elgiushy HR, et al. Among authors: hammad sf. Bioorg Chem. 2022 Mar;120:105646. doi: 10.1016/j.bioorg.2022.105646. Epub 2022 Jan 29. Bioorg Chem. 2022. PMID: 35134645
Novel N-Arylmethyl-aniline/chalcone hybrids as potential VEGFR inhibitors: synthesis, biological evaluations, and molecular dynamic simulations.
Haffez H, Elsayed NA, Ahmed MF, Fatahala SS, Khaleel EF, Badi RM, Elkaeed EB, El Hassab MA, Hammad SF, Eldehna WM, Masurier N, El-Haggar R. Haffez H, et al. Among authors: hammad sf. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2278022. doi: 10.1080/14756366.2023.2278022. Epub 2023 Nov 20. J Enzyme Inhib Med Chem. 2023. PMID: 37982203 Free PMC article.
Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles.
Khayat MT, Zarka MA, El-Telbany DFA, El-Halawany AM, Kutbi HI, Elkhatib WF, Noreddin AM, Khayyat AN, El-Telbany RFA, Hammad SF, Abdel-Naim AB, Alolayan EM, Al-Sawahli MM. Khayat MT, et al. Among authors: hammad sf. Sci Rep. 2022 Sep 8;12(1):15235. doi: 10.1038/s41598-022-18557-2. Sci Rep. 2022. PMID: 36075939 Free PMC article.
77 results