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Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.
Yuan B, Bi C, Tian Y, Wang J, Jin Y, Alsayegh K, Tehseen M, Yi G, Zhou X, Shao Y, Romero FV, Fischle W, Izpisua Belmonte JC, Hamdan S, Huang Y, Li M. Yuan B, et al. Among authors: alsayegh k. BMC Biol. 2024 Apr 29;22(1):101. doi: 10.1186/s12915-024-01896-z. BMC Biol. 2024. PMID: 38685010 Free PMC article.
HLA-based banking of induced pluripotent stem cells in Saudi Arabia.
Alowaysi M, Lehmann R, Al-Shehri M, Baadhaim M, Alzahrani H, Aboalola D, Zia A, Malibari D, Daghestani M, Alghamdi K, Haneef A, Jawdat D, Hakami F, Gomez-Cabrero D, Tegner J, Alsayegh K. Alowaysi M, et al. Among authors: alsayegh k. Stem Cell Res Ther. 2023 Dec 18;14(1):374. doi: 10.1186/s13287-023-03612-0. Stem Cell Res Ther. 2023. PMID: 38111036 Free PMC article.
Generation of iPSC lines (KAIMRCi003A, KAIMRCi003B) from a Saudi patient with Dravet syndrome carrying homozygous mutation in the CPLX1 gene and heterozygous mutation in SCN9A.
Alowaysi M, Al-Shehri M, Badkok A, Attas H, Aboalola D, Baadhaim M, Alzahrani H, Daghestani M, Zia A, Al-Ghamdi K, Al-Ghamdi A, Zakri S, Aouabdi S, Tegner J, Alsayegh K. Alowaysi M, et al. Among authors: alsayegh k. Hum Cell. 2024 Mar;37(2):502-510. doi: 10.1007/s13577-023-01016-z. Epub 2023 Dec 19. Hum Cell. 2024. PMID: 38110787 Free PMC article.
Generation of myoglobin (MB)-knockout human embryonic stem cell (hESC) line (KAIMRCe002-A-1S) using CRISPR/Cas9 technology.
Alowaysi M, Al-Shehri M, Baadhaim M, AlZahrani H, Aboalola D, Daghestani M, Hashem H, Aljahdali R, Salem R, Alharbi A, Muharraq M, Alghamdi K, Alsobiy F, Zia A, Lehmann R, Tegner J, Alsayegh K. Alowaysi M, et al. Among authors: alsayegh k. Stem Cell Res. 2023 Sep;71:103158. doi: 10.1016/j.scr.2023.103158. Epub 2023 Jun 25. Stem Cell Res. 2023. PMID: 37406498 Free article.
Generation of induced pluripotent stem cell Line KAIMRCi001-A by reprogramming erythroid progenitors from peripheral blood of a healthy Saudi donor.
Al-Shehri M, Baadhaim M, Jamalalddin S, Aboalola D, Daghestani M, AlZahrani H, Malibari D, Mubaraki M, Aldubayan K, AlBalwi M, Alsayegh K. Al-Shehri M, et al. Among authors: alsayegh k. Stem Cell Res. 2021 Oct;56:102548. doi: 10.1016/j.scr.2021.102548. Epub 2021 Sep 23. Stem Cell Res. 2021. PMID: 34592601 Free article.
14 results