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Comparison of Wild-Type and High-risk PNPLA3 variants in a Human Biomimetic Liver Microphysiology System for Metabolic Dysfunction-associated Steatotic Liver Disease Precision Therapy.
Xia M, Varmazyad M, Palacin IP, Gavlock DC, Debiasio R, LaRocca G, Reese C, Florentino R, Faccioli LAP, Brown JA, Vernetti LA, Schurdak ME, Stern AM, Gough A, Behari J, Soto-Gutierrez A, Taylor DL, Miedel M. Xia M, et al. Among authors: stern am. bioRxiv [Preprint]. 2024 May 7:2024.04.22.590608. doi: 10.1101/2024.04.22.590608. bioRxiv. 2024. PMID: 38712213 Free PMC article. Preprint.
A metabolic-dysfunction associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system.
Aleman J, Ravikumar K, Wiegand C, Schurdak ME, Vernetti L, Gavlock D, Reese C, DeBiasio R, LaRocca G, Angarita YD, Gough A, Soto-Gutierrez A, Behari J, Yechoor V, Miedel MT, Stern AM, Banerjee I, Taylor DL. Aleman J, et al. Among authors: stern am. bioRxiv [Preprint]. 2024 Apr 30:2024.04.22.590598. doi: 10.1101/2024.04.22.590598. bioRxiv. 2024. PMID: 38712135 Free PMC article. Preprint.
Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors.
Saydmohammed M, Jha A, Mahajan V, Gavlock D, Shun TY, DeBiasio R, Lefever D, Li X, Reese C, Kershaw EE, Yechoor V, Behari J, Soto-Gutierrez A, Vernetti L, Stern A, Gough A, Miedel MT, Lansing Taylor D. Saydmohammed M, et al. Exp Biol Med (Maywood). 2021 Nov;246(22):2420-2441. doi: 10.1177/15353702211009228. Epub 2021 May 6. Exp Biol Med (Maywood). 2021. PMID: 33957803 Free PMC article. Review.
A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies.
Lefever DE, Miedel MT, Pei F, DiStefano JK, Debiasio R, Shun TY, Saydmohammed M, Chikina M, Vernetti LA, Soto-Gutierrez A, Monga SP, Bataller R, Behari J, Yechoor VK, Bahar I, Gough A, Stern AM, Taylor DL. Lefever DE, et al. Among authors: stern am. Metabolites. 2022 Jun 7;12(6):528. doi: 10.3390/metabo12060528. Metabolites. 2022. PMID: 35736460 Free PMC article.
195 results