Ladbury JE - Search Results

1

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation.

Spivak-Kroizman T, Lemmon MA, Dikic I, Ladbury JE, Pinchasi D, Huang J, Jaye M, Crumley G, Schlessinger J, Lax I. Spivak-Kroizman T, et al. Among authors: ladbury je. Cell. 1994 Dec 16;79(6):1015-24. doi: 10.1016/0092-8674(94)90032-9. Cell. 1994. PMID: 7528103

2

Thermodynamic studies of tyrosyl-phosphopeptide binding to the SH2 domain of p56lck.

Lemmon MA, Ladbury JE. Lemmon MA, et al. Among authors: ladbury je. Biochemistry. 1994 May 3;33(17):5070-6. doi: 10.1021/bi00183a010. Biochemistry. 1994. PMID: 7513553

3

Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2.

Lemmon MA, Ladbury JE, Mandiyan V, Zhou M, Schlessinger J. Lemmon MA, et al. Among authors: ladbury je. J Biol Chem. 1994 Dec 16;269(50):31653-8. J Biol Chem. 1994. PMID: 7527391 Free article.

4

Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal.

Ladbury JE, Lemmon MA, Zhou M, Green J, Botfield MC, Schlessinger J. Ladbury JE, et al. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3199-203. doi: 10.1073/pnas.92.8.3199. Proc Natl Acad Sci U S A. 1995. PMID: 7536927 Free PMC article.

5

Two EGF molecules contribute additively to stabilization of the EGFR dimer.

Lemmon MA, Bu Z, Ladbury JE, Zhou M, Pinchasi D, Lax I, Engelman DM, Schlessinger J. Lemmon MA, et al. Among authors: ladbury je. EMBO J. 1997 Jan 15;16(2):281-94. doi: 10.1093/emboj/16.2.281. EMBO J. 1997. PMID: 9029149 Free PMC article.

6

Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.

Kowanetz K, Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K, Taylor JD, Soubeyran P, Engstrom U, Ladbury JE, Dikic I. Kowanetz K, et al. Among authors: ladbury je. J Biol Chem. 2003 Oct 10;278(41):39735-46. doi: 10.1074/jbc.M304541200. Epub 2003 Jul 21. J Biol Chem. 2003. PMID: 12874286 Free article.

7

Inhibition of basal FGF receptor signaling by dimeric Grb2.

Lin CC, Melo FA, Ghosh R, Suen KM, Stagg LJ, Kirkpatrick J, Arold ST, Ahmed Z, Ladbury JE. Lin CC, et al. Among authors: ladbury je. Cell. 2012 Jun 22;149(7):1514-24. doi: 10.1016/j.cell.2012.04.033. Cell. 2012. PMID: 22726438 Free article.

8

Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.

Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE. Ahmed Z, et al. Among authors: ladbury je. J Cell Biol. 2013 Feb 18;200(4):493-504. doi: 10.1083/jcb.201204106. J Cell Biol. 2013. PMID: 23420874 Free PMC article.

9

Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer.

Timsah Z, Ahmed Z, Ivan C, Berrout J, Gagea M, Zhou Y, Pena GN, Hu X, Vallien C, Kingsley CV, Lu Y, Hancock JF, Liu J, Gladden AB, Mills GB, Lopez-Berestein G, Hung MC, Sood AK, Bogdanov M, Ladbury JE. Timsah Z, et al. Among authors: ladbury je. Oncogene. 2016 Apr 28;35(17):2186-96. doi: 10.1038/onc.2015.279. Epub 2015 Jul 27. Oncogene. 2016. PMID: 26212011 Free PMC article.

10

Erythropoietin Stimulates Tumor Growth via EphB4.

Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK. Pradeep S, et al. Among authors: ladbury je. Cancer Cell. 2015 Nov 9;28(5):610-622. doi: 10.1016/j.ccell.2015.09.008. Epub 2015 Oct 17. Cancer Cell. 2015. PMID: 26481148 Free PMC article.

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