Hoyer LW - Search Results

1

Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.

Scandella D, Gilbert GE, Shima M, Nakai H, Eagleson C, Felch M, Prescott R, Rajalakshmi KJ, Hoyer LW, Saenko E. Scandella D, et al. Among authors: hoyer lw. Blood. 1995 Sep 1;86(5):1811-9. Blood. 1995. PMID: 7544643 Free article.

2

Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.

Arai M, Scandella D, Hoyer LW. Arai M, et al. Among authors: hoyer lw. J Clin Invest. 1989 Jun;83(6):1978-84. doi: 10.1172/JCI114107. J Clin Invest. 1989. PMID: 2498393 Free PMC article.

3

Factor VIII inhibitors: structure and function in autoantibody and hemophilia A patients.

Hoyer LW, Scandella D. Hoyer LW, et al. Semin Hematol. 1994 Apr;31(2 Suppl 4):1-5. Semin Hematol. 1994. PMID: 7524160 Review. No abstract available.

4

In hemophilia A and autoantibody inhibitor patients: the factor VIII A2 domain and light chain are most immunogenic.

Scandella DH, Nakai H, Felch M, Mondorf W, Scharrer I, Hoyer LW, Saenko EL. Scandella DH, et al. Among authors: hoyer lw. Thromb Res. 2001 Mar 1;101(5):377-85. doi: 10.1016/s0049-3848(00)00418-7. Thromb Res. 2001. PMID: 11297754

5

A soluble recombinant factor VIII fragment containing the A2 domain binds to some human anti-factor VIII antibodies that are not detected by immunoblotting.

Scandella D, Timmons L, Mattingly M, Trabold N, Hoyer LW. Scandella D, et al. Among authors: hoyer lw. Thromb Haemost. 1992 Jun 1;67(6):665-71. Thromb Haemost. 1992. PMID: 1509407

6

Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII.

Healey JF, Lubin IM, Nakai H, Saenko EL, Hoyer LW, Scandella D, Lollar P. Healey JF, et al. Among authors: hoyer lw. J Biol Chem. 1995 Jun 16;270(24):14505-9. doi: 10.1074/jbc.270.24.14505. J Biol Chem. 1995. PMID: 7540171 Free article.

7

Immunoblot cross-reactivity of factor VIII inhibitors with porcine factor VIII.

Koshihara K, Qian J, Lollar P, Hoyer LW. Koshihara K, et al. Among authors: hoyer lw. Blood. 1995 Sep 15;86(6):2183-90. Blood. 1995. PMID: 7662967 Free article.

8

Transgenic pigs produce functional human factor VIII in milk.

Paleyanda RK, Velander WH, Lee TK, Scandella DH, Gwazdauskas FC, Knight JW, Hoyer LW, Drohan WN, Lubon H. Paleyanda RK, et al. Among authors: hoyer lw. Nat Biotechnol. 1997 Oct;15(10):971-5. doi: 10.1038/nbt1097-971. Nat Biotechnol. 1997. PMID: 9335047

9

Inhibition of human factor VIIIa by anti-A2 subunit antibodies.

Lollar P, Parker ET, Curtis JE, Helgerson SL, Hoyer LW, Scott ME, Scandella D. Lollar P, et al. Among authors: hoyer lw. J Clin Invest. 1994 Jun;93(6):2497-504. doi: 10.1172/JCI117259. J Clin Invest. 1994. PMID: 8200986 Free PMC article.

10

Prevention and treatment of factor VIII inhibitors in murine hemophilia A.

Qian J, Collins M, Sharpe AH, Hoyer LW. Qian J, et al. Among authors: hoyer lw. Blood. 2000 Feb 15;95(4):1324-9. Blood. 2000. PMID: 10666206 Free article.

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