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Ordered accumulation of mutations in HIV protease confers resistance to ritonavir.
Molla A, Korneyeva M, Gao Q, Vasavanonda S, Schipper PJ, Mo HM, Markowitz M, Chernyavskiy T, Niu P, Lyons N, Hsu A, Granneman GR, Ho DD, Boucher CA, Leonard JM, Norbeck DW, Kempf DJ. Molla A, et al. Among authors: leonard jm. Nat Med. 1996 Jul;2(7):760-6. doi: 10.1038/nm0796-760. Nat Med. 1996. PMID: 8673921
The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses.
Markowitz M, Vesanen M, Tenner-Racz K, Cao Y, Binley JM, Talal A, Hurley A, Jin X, Chaudhry MR, Yaman M, Frankel S, Heath-Chiozzi M, Leonard JM, Moore JP, Racz P, Nixon DF, Ho DD. Markowitz M, et al. Among authors: leonard jm. J Infect Dis. 1999 Mar;179(3):527-37. doi: 10.1086/314628. J Infect Dis. 1999. PMID: 9952358 Clinical Trial.
Ritonavir and saquinavir combination therapy for the treatment of HIV infection.
Cameron DW, Japour AJ, Xu Y, Hsu A, Mellors J, Farthing C, Cohen C, Poretz D, Markowitz M, Follansbee S, Angel JB, McMahon D, Ho D, Devanarayan V, Rode R, Salgo M, Kempf DJ, Granneman R, Leonard JM, Sun E. Cameron DW, et al. Among authors: leonard jm. AIDS. 1999 Feb 4;13(2):213-24. doi: 10.1097/00002030-199902040-00009. AIDS. 1999. PMID: 10202827 Clinical Trial.
A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. European-Australian Collaborative Ritonavir Study Group.
Danner SA, Carr A, Leonard JM, Lehman LM, Gudiol F, Gonzales J, Raventos A, Rubio R, Bouza E, Pintado V, et al. Danner SA, et al. Among authors: leonard jm. N Engl J Med. 1995 Dec 7;333(23):1528-33. doi: 10.1056/NEJM199512073332303. N Engl J Med. 1995. PMID: 7477167 Free article. Clinical Trial.
Characterization of viral dynamics in human immunodeficiency virus type 1-infected patients treated with combination antiretroviral therapy: relationships to host factors, cellular restoration, and virologic end points.
Wu H, Kuritzkes DR, McClernon DR, Kessler H, Connick E, Landay A, Spear G, Heath-Chiozzi M, Rousseau F, Fox L, Spritzler J, Leonard JM, Lederman MM. Wu H, et al. Among authors: leonard jm. J Infect Dis. 1999 Apr;179(4):799-807. doi: 10.1086/314670. J Infect Dis. 1999. PMID: 10068574
134 results