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Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration.
Mol Cancer Ther. 2017 Dec;16(12):2677-2688. doi: 10.1158/1535-7163.MCT-16-0674. Epub 2017 Oct 20.
Mol Cancer Ther. 2017.
PMID: 29054982
Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F.
Ma L, Clayton JR, Walgren RA, Zhao B, Evans RJ, Smith MC, Heinz-Taheny KM, Kreklau EL, Bloem L, Pitou C, Shen W, Strelow JM, Halstead C, Rempala ME, Parthasarathy S, Gillig JR, Heinz LJ, Pei H, Wang Y, Stancato LF, Dowless MS, Iversen PW, Burkholder TP.
Ma L, et al. Among authors: gillig jr.
Blood Cancer J. 2013 Apr 12;3(4):e109. doi: 10.1038/bcj.2013.6.
Blood Cancer J. 2013.
PMID: 23584399
Free PMC article.
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Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCbeta.
Faul MM, Gillig JR, Jirousek MR, Ballas LM, Schotten T, Kahl A, Mohr M.
Faul MM, et al. Among authors: gillig jr.
Bioorg Med Chem Lett. 2003 Jun 2;13(11):1857-9. doi: 10.1016/s0960-894x(03)00286-5.
Bioorg Med Chem Lett. 2003.
PMID: 12749884
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(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta.
Jirousek MR, Gillig JR, Gonzalez CM, Heath WF, McDonald JH 3rd, Neel DA, Rito CJ, Singh U, Stramm LE, Melikian-Badalian A, Baevsky M, Ballas LM, Hall SE, Winneroski LL, Faul MM.
Jirousek MR, et al. Among authors: gillig jr.
J Med Chem. 1996 Jul 5;39(14):2664-71. doi: 10.1021/jm950588y.
J Med Chem. 1996.
PMID: 8709095
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Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site.
Leesong M, Henderson BS, Gillig JR, Schwab JM, Smith JL.
Leesong M, et al. Among authors: gillig jr.
Structure. 1996 Mar 15;4(3):253-64. doi: 10.1016/s0969-2126(96)00030-5.
Structure. 1996.
PMID: 8805534
Free article.
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