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Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feed-back loop.
J Clin Invest. 1996 Sep 15;98(6):1441-8. doi: 10.1172/JCI118932.
J Clin Invest. 1996.
PMID: 8823310
Free PMC article.
Clinical Trial.
Chimaeric anti-interleukin 6 monoclonal antibodies in the treatment of advanced multiple myeloma: a phase I dose-escalating study.
van Zaanen HC, Lokhorst HM, Aarden LA, Rensink HJ, Warnaar SO, van der Lelie J, van Oers MH.
van Zaanen HC, et al. Among authors: rensink hj.
Br J Haematol. 1998 Aug;102(3):783-90. doi: 10.1046/j.1365-2141.1998.00835.x.
Br J Haematol. 1998.
PMID: 9722307
Free article.
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Blocking interleukin-6 activity with chimeric anti-IL6 monoclonal antibodies in multiple myeloma: effects on soluble IL6 receptor and soluble gp130.
Van Zaanen HC, Lokhorst HM, Aarden LA, Rensink HJ, Warnaar SO, Van Oers MH.
Van Zaanen HC, et al. Among authors: rensink hj.
Leuk Lymphoma. 1998 Nov;31(5-6):551-8. doi: 10.3109/10428199809057614.
Leuk Lymphoma. 1998.
PMID: 9922045
Clinical Trial.
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Co-stimulation of T cells via CD28 inhibits human IgE production; reversal by pertussis toxin.
Van der Pouw-Kraan CT, Rensink HJ, Rappuoli R, Aarden LA.
Van der Pouw-Kraan CT, et al. Among authors: rensink hj.
Clin Exp Immunol. 1995 Mar;99(3):473-8. doi: 10.1111/j.1365-2249.1995.tb05575.x.
Clin Exp Immunol. 1995.
PMID: 7882571
Free PMC article.
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Apolipoprotein H, a new mediator in the inflammatory changes ensuring in jeopardised human myocardium.
Niessen HW, Lagrand WK, Rensink HJ, Meijer CJ, Aarden L, Hack CE, Visser C.
Niessen HW, et al. Among authors: rensink hj.
J Clin Pathol. 2000 Nov;53(11):863-7. doi: 10.1136/jcp.53.11.863.
J Clin Pathol. 2000.
PMID: 11127271
Free PMC article.
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