Otto MJ - Search Results

1

Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication.

Ladner SK, Otto MJ, Barker CS, Zaifert K, Wang GH, Guo JT, Seeger C, King RW. Ladner SK, et al. Among authors: otto mj. Antimicrob Agents Chemother. 1997 Aug;41(8):1715-20. doi: 10.1128/AAC.41.8.1715. Antimicrob Agents Chemother. 1997. PMID: 9257747 Free PMC article.

2

Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidine.

King RW, Ladner SK, Miller TJ, Zaifert K, Perni RB, Conway SC, Otto MJ. King RW, et al. Among authors: otto mj. Antimicrob Agents Chemother. 1998 Dec;42(12):3179-86. doi: 10.1128/AAC.42.12.3179. Antimicrob Agents Chemother. 1998. PMID: 9835512 Free PMC article.

3

The hepatitis B virus M539V polymerase variation responsible for 3TC resistance also confers cross-resistance to other nucleoside analogues.

Ladner SK, Miller TJ, Otto MJ, King RW. Ladner SK, et al. Among authors: otto mj. Antivir Chem Chemother. 1998 Jan;9(1):65-72. Antivir Chem Chemother. 1998. PMID: 9875378

4

Phenylpropenamide derivatives as inhibitors of hepatitis B virus replication.

Perni RB, Conway SC, Ladner SK, Zaifert K, Otto MJ, King RW. Perni RB, et al. Among authors: otto mj. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2687-90. doi: 10.1016/s0960-894x(00)00544-8. Bioorg Med Chem Lett. 2000. PMID: 11128652

5

Limited sequence diversity of the HIV type 1 protease gene from clinical isolates and in vitro susceptibility to HIV protease inhibitors.

Winslow DL, Stack S, King R, Scarnati H, Bincsik A, Otto MJ. Winslow DL, et al. Among authors: otto mj. AIDS Res Hum Retroviruses. 1995 Jan;11(1):107-13. doi: 10.1089/aid.1995.11.107. AIDS Res Hum Retroviruses. 1995. PMID: 7734183

6

In vitro anti-human immunodeficiency virus (HIV) activity of XM323, a novel HIV protease inhibitor.

Otto MJ, Reid CD, Garber S, Lam PY, Scarnati H, Bacheler LT, Rayner MM, Winslow DL. Otto MJ, et al. Antimicrob Agents Chemother. 1993 Dec;37(12):2606-11. doi: 10.1128/AAC.37.12.2606. Antimicrob Agents Chemother. 1993. PMID: 8109924 Free PMC article.

7

Identification of a clinical isolate of HIV-1 with an isoleucine at position 82 of the protease which retains susceptibility to protease inhibitors.

King RW, Winslow DL, Garber S, Scarnati HT, Bachelor L, Stack S, Otto MJ. King RW, et al. Among authors: otto mj. Antiviral Res. 1995 Sep;28(1):13-24. doi: 10.1016/0166-3542(95)00033-i. Antiviral Res. 1995. PMID: 8585757

8

HIV protease inhibitors.

Winslow DL, Otto MJ. Winslow DL, et al. Among authors: otto mj. AIDS. 1995;9 Suppl A:S183-92. AIDS. 1995. PMID: 8819585 Review. No abstract available.

9

In vitro susceptibility of clinical isolates of HIV-1 to XM323, a non-peptidyl HIV protease inhibitor.

Winslow DL, Mayers D, Scarnati H, Lane J, Bincsik A, Otto MJ. Winslow DL, et al. Among authors: otto mj. AIDS. 1994 Jun;8(6):753-6. doi: 10.1097/00002030-199406000-00005. AIDS. 1994. PMID: 8086132

10

Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450.

Hodge CN, Aldrich PE, Bacheler LT, Chang CH, Eyermann CJ, Garber S, Grubb M, Jackson DA, Jadhav PK, Korant B, Lam PY, Maurin MB, Meek JL, Otto MJ, Rayner MM, Reid C, Sharpe TR, Shum L, Winslow DL, Erickson-Viitanen S. Hodge CN, et al. Among authors: otto mj. Chem Biol. 1996 Apr;3(4):301-14. doi: 10.1016/s1074-5521(96)90110-6. Chem Biol. 1996. PMID: 8807858

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