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Role of RNA in enzymatic activity of the reverse transcriptase of hepatitis B viruses.
Wang GH, Zoulim F, Leber EH, Kitson J, Seeger C. Wang GH, et al. Among authors: seeger c. J Virol. 1994 Dec;68(12):8437-42. doi: 10.1128/JVI.68.12.8437-8442.1994. J Virol. 1994. PMID: 7525990 Free PMC article.
Previously, we demonstrated that the protein-priming activity of the polymerase requires a viral RNA segment, termed epsilon, which serves as a template for the synthesis of a short DNA oligomer that is covalently attached to the reverse transcriptase (G.-H. Wang and C. …
Previously, we demonstrated that the protein-priming activity of the polymerase requires a viral RNA segment, termed epsilon, which serves a …
Novel mechanism for reverse transcription in hepatitis B viruses.
Wang GH, Seeger C. Wang GH, et al. Among authors: seeger c. J Virol. 1993 Nov;67(11):6507-12. doi: 10.1128/JVI.67.11.6507-6512.1993. J Virol. 1993. PMID: 7692081 Free PMC article.
However, in hepatitis B viruses the viral polymerase itself acts as a primer for reverse transcription (G.-H. Wang and C. Seeger, Cell 71:663-670, 1992). We have now demonstrated that in order to prime DNA synthesis, the polymerase binds to an RNA hairpin, which the …
However, in hepatitis B viruses the viral polymerase itself acts as a primer for reverse transcription (G.-H. Wang and C. Seeger …
Hepatitis B virus biology.
Seeger C, Mason WS. Seeger C, et al. Microbiol Mol Biol Rev. 2000 Mar;64(1):51-68. doi: 10.1128/MMBR.64.1.51-68.2000. Microbiol Mol Biol Rev. 2000. PMID: 10704474 Free PMC article. Review.
101 results