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Ordered accumulation of mutations in HIV protease confers resistance to ritonavir.
Molla A, Korneyeva M, Gao Q, Vasavanonda S, Schipper PJ, Mo HM, Markowitz M, Chernyavskiy T, Niu P, Lyons N, Hsu A, Granneman GR, Ho DD, Boucher CA, Leonard JM, Norbeck DW, Kempf DJ. Molla A, et al. Among authors: leonard jm. Nat Med. 1996 Jul;2(7):760-6. doi: 10.1038/nm0796-760. Nat Med. 1996. PMID: 8673921
Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.
Kempf DJ, Marsh KC, Kumar G, Rodrigues AD, Denissen JF, McDonald E, Kukulka MJ, Hsu A, Granneman GR, Baroldi PA, Sun E, Pizzuti D, Plattner JJ, Norbeck DW, Leonard JM. Kempf DJ, et al. Among authors: leonard jm. Antimicrob Agents Chemother. 1997 Mar;41(3):654-60. doi: 10.1128/AAC.41.3.654. Antimicrob Agents Chemother. 1997. PMID: 9056009 Free PMC article.
ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease.
Sham HL, Kempf DJ, Molla A, Marsh KC, Kumar GN, Chen CM, Kati W, Stewart K, Lal R, Hsu A, Betebenner D, Korneyeva M, Vasavanonda S, McDonald E, Saldivar A, Wideburg N, Chen X, Niu P, Park C, Jayanti V, Grabowski B, Granneman GR, Sun E, Japour AJ, Leonard JM, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: leonard jm. Antimicrob Agents Chemother. 1998 Dec;42(12):3218-24. doi: 10.1128/AAC.42.12.3218. Antimicrob Agents Chemother. 1998. PMID: 9835517 Free PMC article. Clinical Trial.
The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses.
Markowitz M, Vesanen M, Tenner-Racz K, Cao Y, Binley JM, Talal A, Hurley A, Jin X, Chaudhry MR, Yaman M, Frankel S, Heath-Chiozzi M, Leonard JM, Moore JP, Racz P, Nixon DF, Ho DD. Markowitz M, et al. Among authors: leonard jm. J Infect Dis. 1999 Mar;179(3):527-37. doi: 10.1086/314628. J Infect Dis. 1999. PMID: 9952358 Clinical Trial.
134 results