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From toxicological problem to therapeutic use: the discovery of the mode of action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug.
Lock EA, Ellis MK, Gaskin P, Robinson M, Auton TR, Provan WM, Smith LL, Prisbylla MP, Mutter LC, Lee DL. Lock EA, et al. Among authors: prisbylla mp. J Inherit Metab Dis. 1998 Aug;21(5):498-506. doi: 10.1023/a:1005458703363. J Inherit Metab Dis. 1998. PMID: 9728330 Review.
Design, synthesis and in vitro evaluation of potent, novel, small molecule inhibitors of plasminogen activator inhibitor-1.
Folkes A, Brown SD, Canne LE, Chan J, Engelhardt E, Epshteyn S, Faint R, Golec J, Hanel A, Kearney P, Leahy JW, Mac M, Matthews D, Prisbylla MP, Sanderson J, Simon RJ, Tesfai Z, Vicker N, Wang S, Webb RR, Charlton P. Folkes A, et al. Among authors: prisbylla mp. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1063-6. doi: 10.1016/s0960-894x(02)00078-1. Bioorg Med Chem Lett. 2002. PMID: 11909718